6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt
6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt (CAS 61255-63-8) is a pH-sensitive fluorescent dye with a molecular weight of 438.34 g/mol. It is soluble in water, methanol, and DMF. This compound is primarily utilised as a fluorescent indicator for measuring intracellular pH (pHi) and for forming charge transfer complexes in studies of nanostructure assembly. It is supplied by TSS with an assay of ≥97.0% (HPCE).
- IUPAC
- DHPDS,Disodium 6,8-dihydroxy-1,3-pyrenedisulfonate
- Synonyms
- 61255-63-8C16H8Na2O8S2Disodium 6,8-dihydroxy-1,3-pyrenedisulfonate

Intracellular pH Measurement
6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt acts as a pH-sensitive fluorescent dye, enabling the measurement of intracellular pH (pHi) in biological systems.
Nanostructure Assembly Studies
The compound is used to create charge transfer complexes, facilitating research into the assembly and properties of nanostructures.
Fluorescent Indicator
Its fluorescent properties make it suitable for applications requiring sensitive detection and visualisation in various biochemical assays.
| Molecular weight | 438.34 |
|---|---|
| Empirical formula | C16H8Na2O8S2 |
| Assay | ≥97.0% (HPCE) |
| Solubility | DMF: solubleH2O: solublemethanol: soluble |
| Application | 6,8-Dihydroxy-1,3-pyrenedisulfonic acid (DHPDS) is a pH-sensitive dye that may be used to measure pH changes inside cells (pHi). DHPDS is used to create charge transfer complexes for studies on nanostructure assembly. |
| Suitability | suitable for fluorescence |
| Melting point | ≥250 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Pka  | 7.338.53 |
| Fluorescence | λex 405 nm; λem 456 nm in 0.1 M citrate pH 3.0λex 458 nm; λem 498 nm in 0.1 M Tris pH 8.0 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt used for?
+
This compound is used as a pH-sensitive fluorescent dye for measuring intracellular pH (pHi) and for creating charge transfer complexes in nanostructure assembly studies.
What is the CAS number and formula for 6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt?
+
The CAS number is 61255-63-8 and the empirical formula (Hill notation) is C16H8Na2O8S2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt with an assay of ≥97.0% (HPCE). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling requirements for this chemical?
+
This compound is classified with GHS07 symbol and 'Warning' signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
How is 6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt packaged and exported?
+
Tech Serve Solutions carefully packages and exports chemicals globally, adhering to all relevant shipping and regulatory standards.
How can I request a quote or sample?
+
To request a quote or a sample, please contact the Tech Serve Solutions sales team through our website or by calling us directly. We are happy to assist with your research needs.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis