6-(4-Acetamido-1,8-naphthalamido)hexanoic acid

CAS 172227-59-7C20H20N2O5Biochemicals & Reagents

6-(4-Acetamido-1,8-naphthalamido)hexanoic acid (CAS: 172227-59-7) is a specialized fluorescent probe with the molecular formula C20H20N2O5. This compound is primarily utilised for the fluorescent labeling of antisense oligonucleotides, making it valuable in biochemical research and molecular biology applications. Its fluorescent properties allow for sensitive detection and tracking in various experimental settings.

IUPAC: 6-(4-Acetamino-1,8-naphthalamido)caproic acid,6-(Acetamido)-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanoic acid
Synonyms: 6-(4-Acetamino-1,8-naphthalamido)caproic acid6-(Acetamido)-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanoic acid

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6-(4-Acetamido-1,8-naphthalamido)hexanoic acid (C20H20N2O5) — chemical structure, CAS 172227-59-7; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsDerivatization agents

01 /Applications

Fluorescent Labeling of Oligonucleotides

This compound serves as a fluorescent probe for labeling antisense oligonucleotides. Its specific spectral properties (λex 364 nm; λem 476 nm) enable sensitive detection in biological assays.

Biochemical Research

As a biochemical reagent, it facilitates advanced research in molecular biology and genetics. Its utility in labeling nucleic acid structures aids in understanding cellular processes and genetic mechanisms.

Derivatization Agent

The compound functions as a derivatization agent, particularly for applications requiring fluorescent detection. This is critical in analytical chemistry and biochemical analysis to enhance signal detection.

02 /Properties

Molecular weight	368.38
Empirical formula	C20H20N2O5
Assay	≥95.0% (HPCE)
Application	6-(4-Acetamido-1,8-naphthalamido)hexanoic acid (6-(4-Acetamino-1,8-naphthalamido)caproic acid, NCA) is a fluorescent probe used for labeling antisense oligonucleotides.
Suitability	suitable for fluorescence

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

172227-59-7

MDL number

MFCD04040049

Beilstein registry

7443686

05 /Additional specifications

Fluorescence	λex 364 nm; λem 476 nm in 0.1 M phosphate pH 7.0

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 6-(4-Acetamido-1,8-naphthalamido)hexanoic acid used for?

This compound is a fluorescent probe utilized for labeling antisense oligonucleotides in biochemical research.

What is the CAS number and molecular formula?

The CAS number is 172227-59-7, and the molecular formula is C20H20N2O5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with a minimum purity of ≥95.0% determined by HPCE. It is suitable for fluorescence applications. TSS does not represent this product as USP, BP, or EP grade.

What are the safety and handling recommendations?

Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling this compound. It carries a WGK Germany rating of 3, indicating a high hazard level.

How is this chemical packed and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging and adherence to international shipping regulations for export.