5-(N-Ethyl-N-isopropyl)amiloride
5-(N-Ethyl-N-isopropyl)amiloride (CAS: 1154-25-2, Formula: C11H18ClN7O, MW: 299.76) is a bioactive small molecule and an amiloride derivative. It acts as an inhibitor of epithelial sodium channels (ENaC) and Na+/K+-ATPase. This compound is primarily used in research settings to investigate ion transport mechanisms and cellular signalling pathways, particularly within neuroscience and cell biology research. It is supplied by Tech Serve Solutions for laboratory and investigational purposes.
- IUPAC
- EIPA
- Synonyms
- EIPA
Ion Channel Research
Utilised as a specific inhibitor of epithelial sodium channels (ENaC) and other related ion transporters. It aids in elucidating the physiological roles of these channels in various cell types and tissues.
Cell Signalling Studies
Serves as a tool to investigate signalling cascades influenced by ion flux, particularly in the context of neuroscience and cardiovascular research. Its effects on Na+/K+-ATPase activity are also a focus of study.
Biochemical Assays
Employed in in vitro assays to study enzyme inhibition, specifically targeting Na+/K+-ATPase and related transport proteins. This helps in understanding enzyme kinetics and mechanism of action.
Pharmacological Research
Investigated for its potential modulatory effects on cellular excitability and transport, contributing to the understanding of drug mechanisms and the development of novel therapeutics targeting ion channels.
| Molecular weight | 299.76 |
|---|---|
| Empirical formula | C11H18ClN7O |
| Storage temperature | 2-8°C |
| Melting point | 202-205 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(N-Ethyl-N-isopropyl)amiloride used for?
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5-(N-Ethyl-N-isopropyl)amiloride is used in research as an inhibitor of epithelial sodium channels (ENaC) and Na+/K+-ATPase. It is applied in studies related to cell signalling, neuroscience, and ion transport mechanisms.
What is the CAS number and formula for 5-(N-Ethyl-N-isopropyl)amiloride?
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The CAS number is 1154-25-2 and the empirical formula is C11H18ClN7O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and laboratory use. The specific grade and purity are available upon request or via the product's Certificate of Analysis. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 5-(N-Ethyl-N-isopropyl)amiloride?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
Is 5-(N-Ethyl-N-isopropyl)amiloride a controlled substance?
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The provided data does not indicate that 5-(N-Ethyl-N-isopropyl)amiloride is a controlled substance.
How is 5-(N-Ethyl-N-isopropyl)amiloride packed, shipped, and exported?
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Products are carefully packed according to industry standards and regulations for safe transport. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or a quote for 5-(N-Ethyl-N-isopropyl)amiloride?
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Please contact our sales team or use the online inquiry form to request a sample or a quote for 5-(N-Ethyl-N-isopropyl)amiloride.
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