5-AIQ hydrochloride
5-AIQ hydrochloride (CAS: 93117-07-8), with the molecular formula C9H9ClN2O and a molecular weight of 196.63 g/mol, is a chemical compound supplied by Tech Serve Solutions. It functions as an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1). Research has indicated that PARP inhibitors, including 5-AIQ hydrochloride, possess antiangiogenic properties, which hold significant potential for therapeutic applications in oncology and the treatment of certain retinopathies.
- IUPAC
- 5-Aminoisoquinolinone hydrochloride
PARP-1 Inhibition
5-AIQ hydrochloride serves as a selective inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1). This enzymatic activity is crucial for understanding DNA repair mechanisms and cellular responses to genotoxic stress.
Oncological Research
Studies have utilized 5-AIQ hydrochloride to investigate the antiangiogenic effects of PARP inhibitors. This research may contribute to the development of novel therapeutic strategies for various types of cancer.
Retinopathy Research
The antiangiogenic properties demonstrated by PARP inhibitors in studies involving 5-AIQ hydrochloride suggest potential applications in understanding and treating certain retinopathies where abnormal blood vessel growth is a factor.
| Molecular weight | 196.63 |
|---|---|
| Empirical formula | C9H9ClN2O |
| Assay | ≥97% (HPLC) |
| Form | solid |
| Colour | tan |
| Solubility | DMSO: >20 mg/mLH2O: >20 mg/mL |
| Storage temperature | −20°C |
| Application | 5-AIQ hydrochloride is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1). 5-AIQ hydrochloride was used in a study that determined PARP inhibitors have antiangiogenic effects, which may have tremendous clinical implications for the treatment of various cancers and certain retinopathies. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-AIQ hydrochloride used for?
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5-AIQ hydrochloride is used as an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1). It has been studied for its antiangiogenic effects, with potential implications in cancer and retinopathy research.
What is the CAS number and chemical formula for 5-AIQ hydrochloride?
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The CAS number for 5-AIQ hydrochloride is 93117-07-8, and its chemical formula is C9H9ClN2O.
What grade and purity does Tech Serve Solutions supply for 5-AIQ hydrochloride?
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Tech Serve Solutions supplies 5-AIQ hydrochloride with an assay of ≥97% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for 5-AIQ hydrochloride?
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5-AIQ hydrochloride is classified with a GHS07 symbol and a Warning signal word. It carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area, avoiding dust formation. Refer to the Safety Data Sheet (SDS) for comprehensive guidance.
How is 5-AIQ hydrochloride packed, shipped, and exported by TSS?
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5-AIQ hydrochloride is typically supplied as a solid, often in tan colour. TSS ensures appropriate packaging for safe transport and export, adhering to all relevant regulations for chemical shipments.
How can I request a sample or quote for 5-AIQ hydrochloride?
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To request a sample or obtain a quote for 5-AIQ hydrochloride, please contact the Tech Serve Solutions sales team through our official website or by phone, providing your contact details and requirements.
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