5-Chlorouracil
5-Chlorouracil (CAS: 1820-81-1; Formula: C4H3ClN2O2; MW: 146.53) is a halogenated pyrimidine derivative. This versatile chemical building block is primarily utilised in chemical synthesis and research applications. Its structural characteristics make it valuable for creating more complex heterocyclic compounds, particularly in areas of medicinal chemistry and organic synthesis research. Tech Serve Solutions offers 5-Chlorouracil with a high purity, suitable for demanding laboratory and industrial processes.
- IUPAC
- 5-Chloro-2,4-dihydroxypyrimidine
Cytotoxicity Assay Control
5-Chlorouracil served as a control substance in resazurin-based cytotoxicity assays. These assays are crucial for evaluating the potential toxicity of compounds in liver cells and hepatocytes.
Heterocyclic Synthesis
As a halogenated heterocycle, 5-Chlorouracil is a valuable intermediate for synthesising various pyrimidine derivatives. Its reactive chlorine atom allows for diverse coupling and substitution reactions.
Organic Synthesis Reagent
This compound functions as a key building block in complex organic synthesis pathways. It is employed in the development of novel molecules and for structure-activity relationship studies.
| Molecular weight | 146.53 |
|---|---|
| Empirical formula | C4H3ClN2O2 |
| Assay | 98% |
| Grade | ReagentPlus® |
| Application | 5-Chlorouracil was used as a control in resazurin-based cytotoxicity assay for screening of cytotoxicity in hepatocytes and liver cell lines1. |
| Melting point | >300 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chlorouracil used for?
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5-Chlorouracil is used in chemical synthesis and as a control in cytotoxicity assays for liver cell lines.
What is the CAS number and molecular formula for 5-Chlorouracil?
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The CAS number is 1820-81-1 and the molecular formula is C4H3ClN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chlorouracil at a minimum assay of 98% with a ReagentPlus® grade. This product is not represented as USP, BP, or EP grade.
What are the safety considerations when handling 5-Chlorouracil?
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Handling 5-Chlorouracil requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 or P1 respirator filter. It is classified with WGK Germany 3.
How is 5-Chlorouracil packaged and shipped?
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5-Chlorouracil is carefully packaged according to international shipping regulations for chemicals and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 5-Chlorouracil?
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Please contact Tech Serve Solutions via our website or direct inquiry channels to request a sample or obtain a quotation for 5-Chlorouracil.
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