5-Cholesten-3-one
5-Cholesten-3-one (CAS: 601-54-7) is a steroidal ketone with the molecular formula C27H44O and a molecular weight of 384.64 g/mol. This compound serves as a valuable intermediate and building block in complex organic synthesis. Its steroidal structure makes it particularly useful in the development of novel steroid derivatives and in stereoselective transformations within advanced chemical research and pharmaceutical development.
- IUPAC
- 3-Keto-5-cholestene

Asymmetric Synthesis
5-Cholesten-3-one is employed as a chiral building block in asymmetric synthesis, enabling the construction of complex stereocenters with high control. Its inherent chirality facilitates the creation of enantiomerically pure target molecules.
Chemical Synthesis Intermediate
This compound acts as a key intermediate in multi-step organic synthesis pathways. It is utilised for the preparation of more complex steroid structures and related compounds in research and development settings.
Chiral Building Block
As a chiral building block, 5-Cholesten-3-one offers a defined stereochemical framework for synthetic chemists. It is instrumental in synthesising molecules where specific stereochemistry is crucial for biological activity or material properties.
Complex Molecule Synthesis
Its steroidal scaffold makes 5-Cholesten-3-one a useful starting material or intermediate in the synthesis of intricate organic molecules, including potential pharmaceutical agents and natural product analogues.
| Molecular weight | 384.64 |
|---|---|
| Empirical formula | C27H44O |
| Melting point | 125-127 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Cholesten-3-one used for?
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5-Cholesten-3-one is primarily used as an intermediate and chiral building block in asymmetric synthesis and the preparation of complex molecules, particularly steroid derivatives, within chemical research and development.
What is the CAS number and formula for 5-Cholesten-3-one?
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The CAS number for 5-Cholesten-3-one is 601-54-7, and its molecular formula is C27H44O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Cholesten-3-one typically as a research or technical grade material. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product specifications.
What are the safety and handling recommendations for 5-Cholesten-3-one?
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Handling 5-Cholesten-3-one requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Please consult the Safety Data Sheet for detailed hazard information and handling procedures.
Is 5-Cholesten-3-one a controlled substance?
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The provided data does not indicate that 5-Cholesten-3-one is a controlled substance.
How is 5-Cholesten-3-one packed and shipped?
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Tech Serve Solutions packs and ships 5-Cholesten-3-one according to industry best practices for chemical export, ensuring product integrity and compliance with shipping regulations.
How can I request a quote or sample of 5-Cholesten-3-one?
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To request a quote or sample of 5-Cholesten-3-one, please contact our sales team through the website or by phone, providing your requirements.
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