5-Chlorovaleric acid
5-Chlorovaleric acid (CAS 1119-46-6) is a halogenated carboxylic acid with the linear formula Cl(CH 2 )<sub>4</sub>COOH and a molecular weight of 136.58 g/mol. This compound serves as a valuable building block in organic synthesis. It is primarily utilised in chemical research and the synthesis of complex organic molecules, finding application in areas such as the preparation of haptens for antibody development.
- IUPAC
- 5-Chloropentanoic acid
- Synonyms
- 5-Chloropentanoic acid
Synthesis of Haptens
5-Chlorovaleric acid has been employed as a derivatising agent for L-hydroxyproline. This reaction facilitates the synthesis of specific haptens, such as HP1 and HP2, which are crucial for developing targeted antibodies.
Organic Building Block
As a functionalised five-carbon chain, it acts as a versatile intermediate in the construction of more complex organic structures. Its applications span various fields within chemical synthesis and research.
Pharmaceutical Intermediate Research
This compound is used in research settings as a starting material or intermediate for exploring new synthetic routes towards potential pharmaceutical agents. Its structure allows for diverse chemical modifications.
| Molecular weight | 136.58 |
|---|---|
| Linear formula | Cl(CH2)4COOH |
| Assay | ≥98.0% (GC) |
| Density | 1.170 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.454(lit.)n20/D 1.454 |
| Storage temperature | 2-8°C |
| Application | 5-Chlorovaleric acid was used to derivatize L-hydroxyproline for the synthesis of haptens HP1 and HP2. These haptens were used in the preparation of antibodies against L-hydroxyproline1. |
| Melting point | 18 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36n20/D 1.454 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chlorovaleric acid used for?
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5-Chlorovaleric acid is used as a building block in organic synthesis, particularly in the preparation of haptens for antibody development and in general chemical synthesis research.
What is the CAS number and formula for 5-Chlorovaleric acid?
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The CAS number is 1119-46-6, and its linear formula is Cl(CH 2 )<sub>4</sub>COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chlorovaleric acid with an assay of ≥98.0% (GC). This product is supplied for research and development purposes and is not represented as USP, EP, or any other pharmacopoeia grade.
How should 5-Chlorovaleric acid be handled safely?
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5-Chlorovaleric acid is classified as a Warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Ensure adequate ventilation and avoid breathing vapours. Refer to the Safety Data Sheet for comprehensive handling guidelines.
Is 5-Chlorovaleric acid a controlled substance?
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Based on the provided data, 5-Chlorovaleric acid is not listed as a controlled substance. However, regulations can vary by region, and users should verify local requirements.
How can I request a quote or sample?
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To request a quote or sample of 5-Chlorovaleric acid, please contact our sales team via the website or through your usual representative. Please specify the quantity required and your delivery location.
How is 5-Chlorovaleric acid packaged and shipped?
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5-Chlorovaleric acid is carefully packaged to ensure stability and safety during transit. We are experienced global suppliers and exporters, adhering to all relevant shipping regulations for chemical products.
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