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5-Chlorothiophene-2-sulfonyl chloride

CAS 2766-74-7C4H2Cl2O2S2Chemical Synthesis

5-Chlorothiophene-2-sulfonyl chloride (CAS: 2766-74-7; Formula: C4H2Cl2O2S2; MW: 217.09) is a halogenated heterocyclic compound. It serves as a valuable building block in organic synthesis, particularly for introducing the 5-chlorothiophene-2-sulfonyl moiety into more complex molecular structures. This reactive intermediate is crucial for the development of novel compounds within the pharmaceutical and agrochemical industries.

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5-Chlorothiophene-2-sulfonyl chloride (C4H2Cl2O2S2) — chemical structure, CAS 2766-74-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC4 to C6Chemical SynthesisHalogenated HeterocyclesHeterocyclic Building BlocksThiophenes More...
01 /Applications

Organic Synthesis Intermediate

This compound functions as a key intermediate in the synthesis of various organic molecules. Its reactive sulfonyl chloride group allows for facile derivatization, enabling the construction of complex structures for research and development.

Pharmaceutical Research

As a heterocyclic building block, 5-Chlorothiophene-2-sulfonyl chloride is employed in the exploratory synthesis of potential drug candidates. The thiophene ring and sulfonyl chloride functionality are common motifs in pharmacologically active compounds.

Agrochemical Development

The compound can be utilised in the design and synthesis of novel agrochemicals, such as pesticides or herbicides. Halogenated heterocycles often exhibit biological activity relevant to crop protection.

Material Science

It may find application in the development of new materials where the incorporation of a thiophene ring system is desired for specific electronic or structural properties.

02 /Properties
Molecular weight217.09
Empirical formulaC4H2Cl2O2S2
Assay96%
Boiling point112-117 °C(lit.)
Density1.623 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.586(lit.)
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-27-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2766-74-7
MDL number
MFCD00051667
PubChem substance
24878721
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Chlorothiophene-2-sulfonyl chloride used for?

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5-Chlorothiophene-2-sulfonyl chloride is primarily used as a versatile building block in organic synthesis for creating complex molecules, particularly in pharmaceutical and agrochemical research.

What are the CAS number and formula for 5-Chlorothiophene-2-sulfonyl chloride?

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The CAS number is 2766-74-7, and the empirical formula is C4H2Cl2O2S2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 5-Chlorothiophene-2-sulfonyl chloride with a minimum assay of 96%. We do not represent this product as USP, BP, or EP grade.

How should 5-Chlorothiophene-2-sulfonyl chloride be handled safely?

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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment, including face shields, chemical-resistant gloves, and respiratory protection. Work should be conducted in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive guidance.

How is 5-Chlorothiophene-2-sulfonyl chloride packed and shipped?

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5-Chlorothiophene-2-sulfonyl chloride is packed according to relevant regulations for hazardous materials (UN 3265, Class 8, Packing Group II) and is available for export worldwide by Tech Serve Solutions.

How can I request a quote or sample for 5-Chlorothiophene-2-sulfonyl chloride?

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To request a quote or sample, please contact our sales team via the website or direct email, providing your contact details and the product CAS number (2766-74-7).

Need 5-Chlorothiophene-2-sulfonyl chloride in a specific grade or volume?