9-Fluorenylmethyl N-hydroxycarbamate
9-Fluorenylmethyl N-hydroxycarbamate (CAS: 190656-01-0) is a chemical compound with the formula C15H13NO3 and a molecular weight of 255.27 g/mol. This reagent is primarily utilised as a protecting group in organic synthesis, particularly in peptide chemistry. Its structure allows for the selective protection and deprotection of amine functionalities, making it a valuable tool for chemists working on complex molecular constructions.
- IUPAC
- N-(9-Fluorenylmethoxycarbonyl)hydroxylamine,N-Fmoc-hydroxylamine
Amine Protection in Peptide Synthesis
9-Fluorenylmethyl N-hydroxycarbamate serves as an efficient reagent for introducing the Fmoc (9-fluorenylmethoxycarbonyl) protecting group onto amine functionalities. This protection strategy is widely employed in solid-phase peptide synthesis to manage reactive amine groups during chain elongation.
Organic Synthesis Reagent
Beyond peptide chemistry, this compound finds application in broader organic synthesis where temporary masking of amines is required. The Fmoc group can be selectively removed under mild basic conditions, preserving other sensitive functional groups in the molecule.
Chemical Biology Research
In chemical biology, researchers may utilise this reagent for modifying biomolecules containing amine groups. This enables the study of biological processes or the development of new probes and therapeutic agents.
| Molecular weight | 255.27 |
|---|---|
| Empirical formula | C15H13NO3 |
| Assay | ≥99.0% |
| Melting point | 164.5 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 9-Fluorenylmethyl N-hydroxycarbamate primarily used for?
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9-Fluorenylmethyl N-hydroxycarbamate is primarily used as a protecting group reagent, particularly for amines in peptide synthesis and general organic synthesis.
What is the CAS number and chemical formula for 9-Fluorenylmethyl N-hydroxycarbamate?
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The CAS number is 190656-01-0, and the chemical formula is C15H13NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 9-Fluorenylmethyl N-hydroxycarbamate with an assay of ≥99.0%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 9-Fluorenylmethyl N-hydroxycarbamate be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure good ventilation. This compound is classified as a skin, eye, and respiratory irritant (H315, H319, H335).
Is 9-Fluorenylmethyl N-hydroxycarbamate a controlled substance?
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The provided data does not indicate that 9-Fluorenylmethyl N-hydroxycarbamate is a controlled substance.
How is 9-Fluorenylmethyl N-hydroxycarbamate packed and shipped?
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We export chemicals globally, adhering to all relevant shipping regulations. Specific packing details can be provided upon request.
How can I request a sample or quote for 9-Fluorenylmethyl N-hydroxycarbamate?
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Please contact our sales team through the website to request a sample or a formal quotation for 9-Fluorenylmethyl N-hydroxycarbamate.
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