9-Fluorenylmethyl 1-benzotriazolyl carbonate
9-Fluorenylmethyl 1-benzotriazolyl carbonate (CAS 82911-71-5), with the molecular formula C21H15N3O3 and a molecular weight of 357.36 g/mol, is a key reagent in organic synthesis. It serves as an effective agent for the protection of amine groups. This compound is widely utilised in peptide chemistry and other synthetic applications where precise control over amino group reactivity is essential, facilitating complex molecular construction.
- IUPAC
- Benzotriazol-1-yl 9-fluorenylmethyl carbonate,Fmoc-OBt
- Synonyms
- Benzotriazol-1-yl 9-fluorenylmethyl carbonateFmoc-OBt
Amine Protection Reagent
Utilised for the introduction of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group onto primary and secondary amines. This protection is crucial in multistep syntheses, particularly in peptide synthesis, allowing for selective deprotection under mild basic conditions.
Peptide Synthesis
A cornerstone reagent in solid-phase and solution-phase peptide synthesis for Fmoc-based strategies. Its reactivity and the orthogonal nature of the Fmoc group enable the stepwise assembly of peptide chains.
Organic Synthesis
Applied in general organic synthesis for temporary amine functionalisation, enabling regioselective reactions and the construction of complex organic molecules in pharmaceutical and fine chemical research.
Chemical Biology and Derivatization
Can be employed in chemical biology for derivatization of biomolecules containing amine functionalities or for creating modified building blocks for biochemical studies.
| Molecular weight | 357.36 |
|---|---|
| Empirical formula | C21H15N3O3 |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Melting point | 178 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 9-Fluorenylmethyl 1-benzotriazolyl carbonate used for?
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9-Fluorenylmethyl 1-benzotriazolyl carbonate is primarily used as a reagent for the introduction of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, especially in peptide synthesis and general organic synthesis for amine protection.
What are the CAS number and formula for this compound?
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The CAS number is 82911-71-5, and its molecular formula is C21H15N3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 98%. This product is supplied for research and development purposes and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for this chemical?
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This compound is classified as a Warning with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Handle in a well-ventilated area.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals globally, adhering to all relevant regulations for safe and secure transit.
How can I request a sample or a quote for 9-Fluorenylmethyl 1-benzotriazolyl carbonate?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing your specific requirements.
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