2-Hydroxyestradiol
2-Hydroxyestradiol (CAS: 362-05-0, C18H24O3) is a steroid hormone with a molecular weight of 288.38 g/mol. It is a form of estrogen, playing a role in biological pathways related to cell signalling and neuroscience. This compound is primarily utilised in research settings for its potential in studying cellular functions and hormonal effects, particularly within cell biology and endocrinology research.
- IUPAC
- 1,3,5(10)-Estratriene-2,3-17β-triol,Estra-1,3,5(10)-triene-2,3,17-triol,NSC 61711
- Synonyms
- 1,3,5(10)-Estratriene-2,3-17β-triolEstra-1,3,5(10)-triene-2,3,17-triolNSC 61711

Research in Endocrinology
Utilised in studies investigating the role and mechanisms of estrogenic compounds within biological systems. Its specific structure allows for targeted research into hormonal pathways.
Cell Biology Studies
Serves as a valuable tool for researchers examining cellular responses and signaling pathways influenced by steroid hormones. It aids in understanding cell growth and differentiation.
Neuroscience Research
Applicable in neurobiological research to explore the impact of estrogenic compounds on the central nervous system. Helps elucidate complex neurotransmitter interactions.
Biochemical Assays
Employed in various biochemical assays to quantify or detect its presence, or to study its interactions with other biomolecules. Its purity ensures reliable experimental outcomes.
| Molecular weight | 288.38 |
|---|---|
| Empirical formula | C18H24O3 |
| Assay | ≥95% (HPLC) |
| Storage temperature | −20°C |

Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Ar(24208) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Hydroxyestradiol used for?
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2-Hydroxyestradiol is primarily used in biochemical and cellular research to study hormonal effects, cell signaling, and related biological pathways, particularly within endocrinology and neuroscience.
What is the CAS number and formula for 2-Hydroxyestradiol?
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The CAS number for 2-Hydroxyestradiol is 362-05-0, and its molecular formula is C18H24O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Hydroxyestradiol with a purity of ≥95% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Hydroxyestradiol be handled safely?
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2-Hydroxyestradiol is classified with GHS08 and a 'Warning' signal word, carrying the hazard statement H351 (Suspected of causing cancer). Appropriate personal protective equipment includes a dust mask (N95), eyeshields, and gloves. Handle in a well-ventilated area and avoid dust formation.
Does Tech Serve Solutions export 2-Hydroxyestradiol?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Hydroxyestradiol.
How can I request a quote or sample for 2-Hydroxyestradiol?
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To request a quote or sample for 2-Hydroxyestradiol, please contact our sales team via the website or listed contact details.
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