9-Fluorenone-4-carbonyl chloride
9-Fluorenone-4-carbonyl chloride (CAS: 7071-83-2) is an organic compound with the formula C14H7ClO2 and a molecular weight of 242.66 g/mol. This acid halide derivative of fluorenone serves as a valuable building block in organic synthesis. It is primarily utilised for the functionalisation of amino acids and in the preparation of various carboxamide derivatives, contributing to the development of novel chemical entities.
- IUPAC
- 9-Oxo-4-fluorenecarbonyl chloride
- Synonyms
- 9-Oxo-4-fluorenecarbonyl chloride
Amino Acid Functionalisation
This compound has been employed to functionalise amino acids in alkaline media. This process is often a precursor step for subsequent analyses, such as enantioresolution by High-Performance Liquid Chromatography (HPLC).
Synthesis of Fluorene Carboxamides
9-Fluorenone-4-carbonyl chloride is a key intermediate in the synthesis of specific organic molecules. An example includes its use in the preparation of <i>N</i>-(2-hydroxyethyl)-9-oxo-9<i>H</i>-fluorene-4 carboxamide.
Organic Synthesis Building Block
As a reactive carbonyl chloride, it functions as a versatile building block in organic synthesis. Its structure allows for the introduction of the fluorenone moiety into various molecular frameworks.
| Molecular weight | 242.66 |
|---|---|
| Empirical formula | C14H7ClO2 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Impurities tested | <2% dichloromethane |
| Application | 9-Fluorenone-4-carbonyl chloride was used to functionalize amino acids in alkaline medium before their enantioresolution by HPLC1. It was also used in the synthesis of N-(2-hydroxyethyl)-9-oxo-9H-fluorene-4 carboxamide2. |
| Melting point | 139-141 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H351Suspected of causing cancer
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-40 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 9-Fluorenone-4-carbonyl chloride used for?
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9-Fluorenone-4-carbonyl chloride is used as a building block in organic synthesis, notably for functionalising amino acids and synthesising carboxamide derivatives.
What are the CAS number and formula for 9-Fluorenone-4-carbonyl chloride?
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The CAS number is 7071-83-2, and the empirical formula is C14H7ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 9-Fluorenone-4-carbonyl chloride with a minimum assay of 97%. This product is not supplied as USP, BP, or EP grade.
How should 9-Fluorenone-4-carbonyl chloride be handled?
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Handling requires caution due to its corrosive nature (H314). It is also suspected of causing cancer (H351). Always use appropriate personal protective equipment (gloves, eye protection, protective clothing) and work in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for full details.
Is 9-Fluorenone-4-carbonyl chloride shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 9-Fluorenone-4-carbonyl chloride, adhering to all relevant shipping regulations.
How can I request a quote or sample for 9-Fluorenone-4-carbonyl chloride?
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To request a quote or sample, please contact our sales team via the website or direct inquiry channels, providing your specific requirements.
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