Triptolide

CAS 38748-32-2C20H24O6Cell Biology

Triptolide (CAS: 38748-32-2, C20H24O6) is a bioactive small molecule derived from Tripterygium wilfordii. With a molecular weight of 360.40 g/mol, this white to off-white solid is primarily utilized in biological research. It acts as a potent NF-κB inhibitor, facilitating studies into cell invasion, angiogenesis, and apoptotic effects within various cancer cell lines, particularly thyroid cancer.

IUPAC: PG 490

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Triptolide (C20H24O6) — chemical structure, CAS 38748-32-2; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyImmune System RegulationNutrition ResearchT More...

01 /Applications

NF-κB Inhibition Studies

Triptolide serves as a valuable NF-κB inhibitor for investigating cellular processes. It has been employed to study the inhibition of cell invasion and angiogenesis in human thyroid cancer cells.

Apoptosis Research

Researchers utilize Triptolide to explore its apoptotic effects. Studies have investigated its role in inducing programmed cell death in anaplastic thyroid cancer cells.

Phytochemical Research

As a phytochemical found in Traditional Chinese Medicine (TCM), Triptolide is a subject of interest in nutrition and herbal medicine research, exploring its bioactive properties.

02 /Properties

Molecular weight	360.40
Empirical formula	C20H24O6
Assay	≥98% (HPLC)
Form	solid
Colour	white to off-white
Solubility	DMSO: soluble
Storage temperature	2-8°C
Application	Triptolide has been used as a NF-κB inhibitor to study the inhibition of cell invasion and angiogenesis in human thyroid cancer cells6. Triptolide has also been used to study its apoptotic effects in anaplastic thyroid cancer cells7.
Biological source	from Tripterygium wilfordii

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

38748-32-2

MDL number

MFCD00210565

PubChem substance

24900156

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Triptolide used for?

Triptolide is used in biological research as an NF-κB inhibitor to study cell invasion, angiogenesis, and apoptotic effects, particularly in cancer cell lines. It is also researched for its properties as a phytochemical.

What are the CAS number and formula for Triptolide?

The CAS number for Triptolide is 38748-32-2, and its empirical formula is C20H24O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Triptolide with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.

What are the safety and handling requirements for Triptolide?

Handling Triptolide requires appropriate personal protective equipment, including eyeshields and gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It has a WGK rating of 3 in Germany, indicating a high hazard level.

How is Triptolide packed, shipped, and exported?

Triptolide is typically stored at 2-8°C. Tech Serve Solutions, as a global supplier, adheres to strict international shipping regulations for chemical export.