Trilostane

CAS 13647-35-3C20H27NO3Cell Biology

Trilostane (CAS: 13647-35-3; C20H27NO3; MW: 329.43) is a chemical compound classified as a corticosteroid. It functions by inhibiting the activity of 3β-hydroxysteroid dehydrogenase. This property makes it a valuable tool in biological research for studying steroidogenesis and related pathways, particularly within endocrine and cell biology research settings.

IUPAC: (4α,5α,17β)-3,17-dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile

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Trilostane (C20H27NO3) — chemical structure, CAS 13647-35-3; Life Science, fine chemical supplied by Tech Serve Solutions

AndrogenBioactive Small MoleculesCell BiologyCorticosteroidCytokinesGrowth Factors and HormonesHormonesSteroid HormonesT More...

01 /Applications

Research in Steroidogenesis

Trilostane is utilised in laboratory research to inhibit the 3β-hydroxysteroid dehydrogenase enzyme, a critical component in the biosynthesis of corticosteroids and androgens. This inhibition allows researchers to investigate the downstream effects of reduced steroid hormone production.

Cellular Biology Studies

It serves as a bioactive small molecule in cell biology studies, enabling the investigation of cellular responses to altered steroidogenic pathways. This includes examining the impact on various cell types, such as those found in the ovaries.

Endocrinology Research Tool

As a corticosteroid inhibitor, Trilostane is employed in endocrinology research to probe the complex mechanisms of the endocrine system and hormone signaling pathways.

02 /Properties

Molecular weight	329.43
Empirical formula	C20H27NO3
Assay	≥98% (HPLC)
Form	powder
Colour	white to tan
Solubility	DMSO: ≥17 mg/mL
Storage temperature	2-8°C
Application	Trilostane was used to inhibit the activity of 3β-hydroxysteroid dehydrogenase in mouse ovary.1

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements

P281Use personal protective equipment as required
P305IF IN EYES

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38-62
Safety statements (S)	26-36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

13647-35-3

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Trilostane used for?

Trilostane is used in research to inhibit the activity of 3β-hydroxysteroid dehydrogenase, aiding in the study of steroidogenesis and related biological pathways.

What is the CAS number and formula for Trilostane?

The CAS number for Trilostane is 13647-35-3, and its empirical formula is C20H27NO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Trilostane with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should Trilostane be handled and stored?

Trilostane is a Warning substance that can cause skin irritation (H315), serious eye irritation (H319), and may damage fertility or the unborn child (H361). It should be handled with appropriate personal protective equipment in a well-ventilated area and stored at 2-8°C.

How is Trilostane packed and exported?

Trilostane is available as a white to tan powder. As a global supplier, Tech Serve Solutions exports this chemical, adhering to all relevant shipping regulations.