5-Chlorovaleroyl chloride
5-Chlorovaleroyl chloride (CAS: 1575-61-7), with the linear formula Cl(CH2)4COCl and a molecular weight of 155.02 g/mol, is an acyl halide. This compound serves as a versatile building block in organic synthesis. It is primarily employed in the preparation of various organic intermediates and in the development of specialised materials, such as anion-exchange resins. Its reactivity makes it a valuable reagent for acylation reactions in chemical research and development.
- IUPAC
- 5-Chloropentanoyl chloride
- Synonyms
- 5-Chloropentanoyl chloride
Synthesis of Anion-Exchange Resins
5-Chlorovaleroyl chloride is utilized in the synthesis of anion-exchange resins through a process involving the acylation of polystyrene/divinylbenzene followed by amination with trimethylamine. This application contributes to the development of materials for separation and purification processes.
Analytical Method Development
This compound has been employed in the development and validation of analytical methods, specifically a GC-FID technique designed for the accurate quantification of low-level impurities present within 5-Chlorovaleroyl chloride itself.
Organic Synthesis Intermediate
As a functionalised acyl chloride, 5-Chlorovaleroyl chloride acts as a key intermediate in organic synthesis, enabling the introduction of the 5-chloropentanoyl group into various molecular structures for further chemical transformations.
| Molecular weight | 155.02 |
|---|---|
| Linear formula | Cl(CH2)4COCl |
| Assay | ≥97.0% (T) |
| Boiling point | 38-39 °C/0.15 mmHg(lit.) |
| Density | 1.206 g/mL at 20 °C1.2 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.464(lit.)n20/D 1.464 |
| Application | 5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC1. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine2. |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chlorovaleroyl chloride used for?
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5-Chlorovaleroyl chloride is used as a building block in organic synthesis, particularly for the preparation of anion-exchange resins and in the development of analytical methods for impurity analysis. It is a versatile reagent for acylation reactions in chemical research.
What is the CAS number and chemical formula for 5-Chlorovaleroyl chloride?
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The CAS number for 5-Chlorovaleroyl chloride is 1575-61-7. Its linear chemical formula is Cl(CH2)4COCl.
What grade and purity does Tech Serve Solutions supply for 5-Chlorovaleroyl chloride?
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Tech Serve Solutions supplies 5-Chlorovaleroyl chloride with an assay of ≥97.0% (T). We do not represent this product as USP, BP, EP, or any pharmacopoeial grade.
How should 5-Chlorovaleroyl chloride be handled safely?
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5-Chlorovaleroyl chloride is classified as dangerous. It causes severe skin burns and eye damage (H314) and is harmful if swallowed (H302). Appropriate personal protective equipment, including face shields, gloves, goggles, and suitable respirators, must be worn. Handle only in well-ventilated areas and follow strict safety protocols.
Is 5-Chlorovaleroyl chloride available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Chlorovaleroyl chloride, catering to international clients.
How can I request a quote or sample for 5-Chlorovaleroyl chloride?
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To request a quote or sample for 5-Chlorovaleroyl chloride, please contact our sales team through the website or designated contact channels, providing your specific requirements.
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