5-Chlorothiophene-2-sulfonamide
5-Chlorothiophene-2-sulfonamide (CAS: 53595-66-7), with the molecular formula C4H4ClNO2S2 and a molecular weight of 197.66 g/mol, is a halogenated heterocyclic compound. It serves as a valuable building block in chemical synthesis, particularly within organic and medicinal chemistry research. This compound is a key intermediate for constructing more complex molecular architectures. Its utility lies in its reactive functional groups, enabling diverse chemical transformations.

Chemical Synthesis Intermediate
5-Chlorothiophene-2-sulfonamide is utilised as a fundamental building block in organic synthesis. It enables the introduction of the thiophene-sulfonamide moiety into larger molecules, facilitating the creation of novel chemical entities.
Medicinal Chemistry Research
The compound serves as an intermediate in the development of potential pharmaceutical agents. Its structure can be modified to explore new drug candidates and therapeutic applications.
Heterocyclic Chemistry
As a halogenated thiophene derivative, it is employed in studies focused on the synthesis and reactivity of heterocyclic compounds, expanding the scope of known chemical structures.
| Molecular weight | 197.66 |
|---|---|
| Empirical formula | C4H4ClNO2S2 |
| Assay | 97% |
| Melting point | 113-117 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chlorothiophene-2-sulfonamide used for?
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5-Chlorothiophene-2-sulfonamide (CAS: 53595-66-7) is primarily used as a building block and intermediate in organic synthesis and medicinal chemistry research.
What are the CAS number and formula for 5-Chlorothiophene-2-sulfonamide?
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The CAS number is 53595-66-7, and the empirical formula is C4H4ClNO2S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chlorothiophene-2-sulfonamide with a minimum assay of 97%. This is a technical or research grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Chlorothiophene-2-sulfonamide be handled?
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Handling requires precautions against dust inhalation, eye contact, and skin contact. Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do. Continue rinsing.
Is 5-Chlorothiophene-2-sulfonamide a controlled substance?
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Based on the provided data, there is no indication that 5-Chlorothiophene-2-sulfonamide is a controlled substance.
How is 5-Chlorothiophene-2-sulfonamide packed, shipped, and exported?
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Tech Serve Solutions, a global supplier since 1998, expertly packs, ships, and exports fine chemicals worldwide, adhering to all necessary regulations for safe and compliant international transit.
How can I request a sample or quote for 5-Chlorothiophene-2-sulfonamide?
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To request a sample or a quote for 5-Chlorothiophene-2-sulfonamide, please contact our sales team through the website or provide your requirements via email.
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