(−)-trans-Caryophyllene
(−)-trans-Caryophyllene, CAS 87-44-5, is a bicyclic sesquiterpene with the molecular formula C15H24 and a molecular weight of 204.35 g/mol. This compound is naturally found in many plants and is known for its distinctive aroma. It serves as a valuable building block in chemical synthesis and is used in research related to cell biology and asymmetric synthesis.
- IUPAC
- β-Caryophyllene,trans-(1R,9S)-8-Methylene-4,11,11-trimethylbicyclo[7.2.0]undec-4-ene

Chemical Synthesis
As a bicyclic sesquiterpene, (–)-trans-Caryophyllene is a useful starting material or intermediate in various organic synthesis pathways. Its chiral nature makes it particularly interesting for asymmetric synthesis.
Cell Biology Research
This compound is employed in studies investigating cellular mechanisms and responses. Its presence in various natural sources suggests potential biological activities that are areas of ongoing research.
Natural Product Analysis
It is a key component of essential oils from numerous plants, including clove, rosemary, and hops. It is used as a reference standard and for analytical studies of these natural products.
| Molecular weight | 204.35 |
|---|---|
| Empirical formula | C15H24 |
| Assay | ≥98.5% (sum of enantiomers, GC) |
| Boiling point | 262-264 °C(lit.) |
| Density | 0.902 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.499 |
| Optical activity | [α]20/D −10±1°, neat |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | 96 °C / 204.8 °F |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-trans-Caryophyllene used for?
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(–)-trans-Caryophyllene is used in chemical synthesis, particularly asymmetric synthesis, and in research related to cell biology and natural product analysis.
What are the CAS number and formula for (–)-trans-Caryophyllene?
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The CAS number is 87-44-5, and the molecular formula is C15H24.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-trans-Caryophyllene with an assay of ≥98.5% (sum of enantiomers, GC). This is a research-grade chemical, and TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations for handling (–)-trans-Caryophyllene?
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Handle (–)-trans-Caryophyllene with appropriate personal protective equipment, including eyeshields and gloves. It has a flash point of 96 °C (204.8 °F).
How is (–)-trans-Caryophyllene packed and shipped?
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Tech Serve Solutions packs and ships chemicals according to international regulations, ensuring safe delivery globally. Specific packaging details are available upon request.
How can I request a quote or sample of (–)-trans-Caryophyllene?
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To request a quote or sample, please contact our sales department through the website or by phone.
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