(−)-tert-Butyl (S)-2-hydroxybutyrate
(−)-tert-Butyl (S)-2-hydroxybutyrate (CAS: 37787-90-9), a chiral building block with the linear formula C2H5CH(OH)CO2C(CH3)3, has a molecular weight of 160.21 g/mol. This ester is primarily utilised in asymmetric synthesis and organic chemical synthesis. Its defined stereochemistry makes it a valuable intermediate for constructing complex molecules with specific spatial arrangements, particularly in the pharmaceutical and fine chemical industries.
Asymmetric Synthesis
Serves as a chiral synthon in asymmetric synthesis, enabling the stereoselective formation of new chiral centres. Its defined (S)-configuration is crucial for building enantiomerically pure target molecules.
Pharmaceutical Intermediates
Utilised as a building block in the synthesis of active pharmaceutical ingredients (APIs) where precise stereochemistry is essential for drug efficacy and safety.
Organic Synthesis
A versatile reagent in general organic synthesis, providing a readily available source of a chiral secondary alcohol moiety protected as a tert-butyl ester.
Chiral Pool Synthesis
Incorporated into chiral pool strategies to introduce chirality into more complex organic structures from readily available chiral starting materials.
| Molecular weight | 160.21 |
|---|---|
| Linear formula | C2H5CH(OH)CO2C(CH3)3 |
| Assay | 98% |
| Optical activity | [α]20/D −5.1°, c = 2 in carbon tetrachloride |
| Optical purity | ee: 98% (GLC) |
| Melting point | 50-54 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-tert-Butyl (S)-2-hydroxybutyrate used for?
+
(–)-tert-Butyl (S)-2-hydroxybutyrate is primarily used in asymmetric synthesis and organic chemical synthesis as a chiral building block.
What is the CAS number and chemical formula for (–)-tert-Butyl (S)-2-hydroxybutyrate?
+
The CAS number is 37787-90-9 and the linear formula is C2H5CH(OH)CO2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (–)-tert-Butyl (S)-2-hydroxybutyrate with an assay of 98% and an optical purity of ee: 98% (GLC). TSS does not represent this product as USP, BP, or EP grade.
How should (–)-tert-Butyl (S)-2-hydroxybutyrate be handled safely?
+
Safe handling requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended for respiratory protection. It is classified under WGK 2 in Germany.
Is (–)-tert-Butyl (S)-2-hydroxybutyrate suitable for pharmaceutical manufacturing?
+
While used as an intermediate in pharmaceutical synthesis, the specific grade supplied is 98% assay and 98% ee, and is not certified to pharmacopoeial standards (USP, BP, EP).
How is (–)-tert-Butyl (S)-2-hydroxybutyrate packed, shipped, and exported?
+
Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and adherence to all regulations for the safe and compliant shipment and export of chemicals.
How can I request a sample or quote for (–)-tert-Butyl (S)-2-hydroxybutyrate?
+
To request a sample or a quote, please contact the TSS sales team through the website or by direct inquiry, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis