5(6)-Carboxy-2′,7′-dichlorofluorescein
5(6)-Carboxy-2′,7′-dichlorofluorescein (CAS: 111843-78-8), with the empirical formula C21H10Cl2O7 and a molecular weight of 445.21 g/mol, is a fluorescent probe. It is specifically utilised as a substrate to investigate the identity, activity, and specificity of multidrug resistance protein 2 (MRP2) molecules. Its fluorescent properties make it valuable in various detection and biochemical research applications.
- Synonyms
- C21H10Cl2O7
MRP2 Protein Studies
Utilised as a specific substrate and fluorescent probe to study the identity, activity, and specificity of multidrug resistance protein 2 (MRP2) molecules in biological research.
Fluorescent Detection
Serves as a fluorescent indicator and probe, suitable for fluorescence-based detection methods in biochemical and diagnostic assays.
pH Sensitive Probes
Functions as a pH sensitive probe, with a reported pKa of 5.1, making it useful in applications requiring pH monitoring or where pH influences fluorescence.
| Molecular weight | 445.21 |
|---|---|
| Empirical formula | C21H10Cl2O7 |
| Assay | ≥95% (TLC) |
| Solubility | DMF: solubleDMSO: solubleH2O: soluble (pH ≥ 5) |
| Application | 5(6)-Carboxy-2′,7′-dichlorofluorescein may be used as a specific substrate/probe to study the identity, activity and specificity of multidrug resistance protein 2 (MRP2) molecules. |
| Suitability | suitable for fluorescence |
| Melting point | ≥250 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Pka  | 5.1 |
| Fluorescence | λex 504 nm; λem 529 nm in 0.1 M Tris pH 8.0 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5(6)-Carboxy-2′,7′-dichlorofluorescein used for?
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5(6)-Carboxy-2′,7′-dichlorofluorescein is primarily used as a specific substrate and fluorescent probe to study the identity, activity, and specificity of multidrug resistance protein 2 (MRP2) molecules.
What are the CAS number and chemical formula for this compound?
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The CAS number for 5(6)-Carboxy-2′,7′-dichlorofluorescein is 111843-78-8, and its empirical formula is C21H10Cl2O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5(6)-Carboxy-2′,7′-dichlorofluorescein with an assay of ≥95% (TLC). This product is not represented as USP, BP, or EP grade.
How should 5(6)-Carboxy-2′,7′-dichlorofluorescein be handled safely?
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As indicated by GHS07, this compound is a warning substance and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use in a well-ventilated area with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves.
Is 5(6)-Carboxy-2′,7′-dichlorofluorescein available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote?
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To request a sample or obtain a quote for 5(6)-Carboxy-2′,7′-dichlorofluorescein, please contact our sales team directly through our website or by phone.
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