4-(Trifluoromethyl)pyridine
4-(Trifluoromethyl)pyridine (CAS: 3796-24-5, C6H4F3N, MW: 147.10) is a versatile fluorinated pyridine derivative. This compound serves as a key building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique trifluoromethyl group imparts specific electronic and lipophilic properties, making it valuable for modifying molecular behaviour. Tech Serve Solutions offers this high-purity reagent for research and development purposes.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs). The trifluoromethylpyridine motif is incorporated into drug candidates to enhance metabolic stability and bioavailability.
Agrochemical Development
Serves as a precursor for novel pesticides and herbicides. The fluorine atoms can increase the efficacy and environmental persistence of agrochemical products.
Material Science Research
Investigated for applications in functional materials, owing to the electronic properties conferred by the trifluoromethyl group and the pyridine ring.
Organic Synthesis Building Block
A valuable reagent for introducing the 4-(trifluoromethyl)pyridyl moiety into diverse organic molecules through various coupling and functionalisation reactions.
| Molecular weight | 147.10 |
|---|---|
| Empirical formula | C6H4F3N |
| Assay | 97% |
| Boiling point | 110 °C(lit.) |
| Density | 1.27 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.417(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 20 °C / 68 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)pyridine used for?
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4-(Trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, especially for creating novel pharmaceuticals and agrochemicals. It is also investigated for applications in material science.
What are the CAS number and formula for 4-(Trifluoromethyl)pyridine?
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The CAS number for 4-(Trifluoromethyl)pyridine is 3796-24-5, and its molecular formula is C6H4F3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)pyridine with a minimum assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How is 4-(Trifluoromethyl)pyridine handled and shipped?
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4-(Trifluoromethyl)pyridine is a flammable liquid and irritant. It should be handled with appropriate personal protective equipment, including safety glasses, gloves, and a respirator, in a well-ventilated area. It is classified as UN 1993, Class 3, Packing Group II for transport.
Can I request a quote or sample for 4-(Trifluoromethyl)pyridine?
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Yes, you can request a quote or sample for 4-(Trifluoromethyl)pyridine through the Tech Serve Solutions website or by contacting our sales team directly.
Is 4-(Trifluoromethyl)pyridine a controlled substance?
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Based on the provided data, 4-(Trifluoromethyl)pyridine is not listed as a controlled substance.
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