Phosphonoacetic acid
Phosphonoacetic acid (CAS: 4408-78-0), with the linear formula (HO)2P(O)CH2CO2H and a molecular weight of 140.03 g/mol, is a versatile chemical compound. It serves as a critical enzyme inhibitor, particularly noted for its role in blocking viral DNA replication. Additionally, it functions as a phosphorus source for microbial growth, enabling growth in phosphate-independent conditions. Supplied by Tech Serve Solutions with an assay of 98%.
Inhibition of Viral DNA Replication
Phosphonoacetic acid has been utilised as an effective inhibitor of viral DNA replication. It aids in research to understand viral processes, such as investigating the localization of infected cell protein 0 (bICP0) in infected bovine cells.
Microbial Growth Studies
This compound serves as a vital phosphorus source for microbial cultures. Its unique property allows for microbial growth in environments lacking traditional phosphate, facilitating research in diverse microbiological settings.
Biochemical Research
As an enzyme inhibitor and organic building block, Phosphonoacetic acid is a valuable reagent in biochemical and chemical synthesis research. It is employed to study enzyme mechanisms and develop new synthetic pathways.
| Molecular weight | 140.03 |
|---|---|
| Linear formula | (HO)2P(O)CH2CO2H |
| Assay | 98% |
| Solubility | water: soluble100 mg/mL, clear to very slightly hazy, colorless |
| Application | Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells1. It was also used as a phosphorus source for microbial growth in phosphate-independent manner2. |
| Melting point | 143-146 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phosphonoacetic acid used for?
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Phosphonoacetic acid is primarily used as an inhibitor of viral DNA replication and as a phosphorus source for microbial growth. It also finds application in biochemical research and chemical synthesis.
What is the CAS number and formula for Phosphonoacetic acid?
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The CAS number for Phosphonoacetic acid is 4408-78-0, and its linear formula is (HO)2P(O)CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phosphonoacetic acid with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Phosphonoacetic acid be handled safely?
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Phosphonoacetic acid is classified as harmful if swallowed (H302). When handling, it is recommended to use a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid ingestion.
Is Phosphonoacetic acid a controlled substance?
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The provided data does not indicate that Phosphonoacetic acid is a controlled substance.
How are Tech Serve Solutions' chemicals packed and exported?
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Tech Serve Solutions packs and exports chemicals according to international shipping regulations, ensuring safe and compliant transit globally. Specific packaging details are available upon request.
How can I request a sample or quote for Phosphonoacetic acid?
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To request a sample or a quote for Phosphonoacetic acid, please contact our sales team through the website or by phone. We are ready to assist with your specific requirements.
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