(S)-RuCl[(p-cymene(BINAP)]Cl
(S)-RuCl[(p-cymene)(BINAP)]Cl, CAS 130004-33-0, is a ruthenium-based chiral catalyst with the formula [C54H46ClP2Ru]+Cl- and a molecular weight of 928.87 g/mol. This complex is instrumental in asymmetric synthesis, facilitating the creation of enantiomerically enriched compounds. It is particularly recognised for its role in catalysing reactions where stereoselectivity is critical, making it valuable in pharmaceutical and fine chemical manufacturing.
- IUPAC
- Chloro[(S)-(−)-2,2′-bis(diphenylphosphino)-1,1′−binaphthyl](p-cymene)ruthenium(II) chloride
![(S)-RuCl[(p-cymene(BINAP)]Cl ([C54H46ClP2Ru]+Cl-) — chemical structure, CAS 130004-33-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F130004-33-0.png&w=3840&q=75)
Asymmetric Hydrogenation
This ruthenium complex serves as a highly effective chiral catalyst for asymmetric hydrogenation reactions. It enables the selective synthesis of chiral molecules, which is crucial in the pharmaceutical industry for producing enantiomerically pure active pharmaceutical ingredients (APIs).
Chiral Ligand in Catalysis
As a complex incorporating the BINAP ligand, it functions as a privileged chiral catalyst. It is employed in various transition-metal catalysed reactions where the precise control of stereochemistry is essential for product efficacy and safety.
Synthesis of Fine Chemicals
The compound is utilised in the synthesis of complex organic molecules and fine chemicals. Its ability to induce chirality allows for the efficient production of enantiopure building blocks for advanced materials and specialty chemicals.
| Molecular weight | 928.87 |
|---|---|
| Linear formula | [C54H46ClP2Ru]+Cl- |
| Storage temperature | 2-8°C |
| Application | Takasago Ligands and Complexes for Asymmetric Reactions |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-RuCl[(p-cymene)(BINAP)]Cl used for?
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(S)-RuCl[(p-cymene)(BINAP)]Cl is primarily used as a chiral catalyst in asymmetric synthesis, particularly for hydrogenation reactions requiring high enantioselectivity in the production of chiral molecules for pharmaceuticals and fine chemicals.
What is the CAS number and chemical formula for this product?
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The CAS number is 130004-33-0 and the chemical formula is [C54H46ClP2Ru]+Cl-.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and development purposes. The specific assay is not provided in detailed pharmacopoeia grades (e.g., USP, EP, BP). Customers should assume a technical or research grade unless otherwise specified, and TSS does not represent it as pharmacopoeia compliant.
How should (S)-RuCl[(p-cymene)(BINAP)]Cl be handled safely?
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This compound is classified as a Warning, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions expertly handles the packing, shipping, and global export of chemicals, ensuring compliance with all international regulations. We maintain strict quality control throughout the logistics process.
How can I request a sample or quote for this product?
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To request a sample or a detailed quote for (S)-RuCl[(p-cymene)(BINAP)]Cl, please contact our sales team through our website or by phone. Provide the product name and CAS number for prompt service.
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