Phosphorus pentachloride
Phosphorus pentachloride (CAS: 10026-13-8, Formula: PCl5, MW: 208.24) is a highly reactive chlorinating agent. It is a solid compound known for its corrosive nature and tendency to react violently with water. Phosphorus pentachloride is indispensable in organic synthesis for the conversion of carboxylic acids into acid chlorides and in the production of phosphorus oxychloride and other organophosphorus compounds.
- IUPAC
- Phosphorus(V) chloride

Organic Synthesis Reagent
Phosphorus pentachloride serves as a key reagent for transforming carboxylic acids into their corresponding acid chlorides, a vital step in the synthesis of esters, amides, and acid anhydrides.
Chlorination Agent
It is extensively used as a chlorinating agent in various chemical transformations, enabling the substitution of oxygen atoms with chlorine, particularly in the synthesis of phosphorus oxychloride.
Production of Organophosphorus Compounds
This compound facilitates the synthesis of a wide array of organophosphorus compounds, which find applications in pharmaceuticals, agrochemicals, and flame retardants.
| Molecular weight | 208.24 |
|---|---|
| Linear formula | PCl5 |
| Assay | ≥98.0% (AT) |
| Grade | reagent grade |
| Impurities tested | ≤0.005% total of sulfur (S) |



Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1806 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 14-22-26-34-48/20 |
| Safety statements (S) | 7/8-26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
| Cation traces | Ca: ≤50 mg/kgCd: ≤50 mg/kgCo: ≤50 mg/kgCu: ≤50 mg/kgFe: ≤50 mg/kgK: ≤100 mg/kgNa: ≤100 mg/kgNi: ≤50 mg/kgPb: ≤50 mg/kgZn: ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phosphorus pentachloride used for?
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Phosphorus pentachloride (CAS: 10026-13-8) is primarily used as a chlorinating agent in organic synthesis for converting carboxylic acids to acid chlorides and in the production of phosphorus oxychloride and other organophosphorus compounds.
What are the CAS number and formula for Phosphorus pentachloride?
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The CAS number for Phosphorus pentachloride is 10026-13-8, and its chemical formula is PCl5.
What grade and purity does Tech Serve Solutions supply for Phosphorus pentachloride?
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Tech Serve Solutions supplies Phosphorus pentachloride in reagent grade with an assay of ≥98.0% (AT). We do not represent this product as USP, BP, or EP grade.
How should Phosphorus pentachloride be handled safely?
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Phosphorus pentachloride is a corrosive substance that reacts violently with water. It is harmful if swallowed, causes severe skin burns and eye damage, and is fatal if inhaled. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3 filters), must be used in a well-ventilated area.
How is Phosphorus pentachloride packed and exported?
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Phosphorus pentachloride is classified under UN 1806, Hazard Class 8, Packing Group II. TSS ensures appropriate packaging for safe handling, shipping, and export in compliance with international regulations.
How can I request a quote or sample of Phosphorus pentachloride?
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To request a quote or a sample of Phosphorus pentachloride, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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