Sulfur trioxide triethylamine complex

CAS 761-01-3(CH3CH2)3N · SO3Chemical Synthesis

Sulfur trioxide triethylamine complex (CAS 761-01-3) is a chemical reagent with the linear formula (CH3CH2)3N · SO3 and a molecular weight of 181.25 g/mol. This compound serves as a key reactant in various synthetic pathways. Its applications include the preparation of anticoagulants, anticancer agents, and specialised drug delivery systems, highlighting its significance in pharmaceutical research and development.

IUPAC: NSC 68185,NSC 8168,Triethylamine sulfur trioxide complex
Synonyms: Triethylamine sulfur trioxide complex

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Sulfur trioxide triethylamine complex ((CH3CH2)3N · SO3) — chemical structure, CAS 761-01-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisOxidizing AgentsSulfur-BasedSynthetic Reagents

01 /Applications

Synthesis of Anticoagulant and Antiplatelet Agents

Utilised as a reactant for the synthesis of persulfated glycosides or flavonoids containing an oligopolysulfated moiety, important for anticoagulant and antiplatelet applications.

Preparation of Anticancer Agents

Serves as a reagent in the synthesis of narciclasine derivatives, which are being investigated for their potential as anticancer agents.

Development of Colon-Specific Prodrugs

Employed in the synthesis of sulfate-conjugated methylprednisolone and dexamethasone 21-sulfate sodium, designed for targeted drug delivery to the colon.

Glycosylation for Biological Substrates

Used in the glycosylation of disaccharides to create tetrasaccharide substrates of heparanase and synthetic heparin oligosaccharide microarrays for studying heparin-protein interactions.

02 /Properties

Molecular weight	181.25
Linear formula	(CH3CH2)3N · SO3
Assay	≥95% sulfur basis (ICP)
Grade	technical
Storage temperature	2-8°C
Application	Reactant for reagent for synthesis of:• Anticoagulant and antiplatelet persulfated glycosides1 or flavonoids containing an oligopolysulfated moiety2• Narciclasine derivatives for use as anticancer agents3• Sulfate-conjugated methylprednisolone for use as a colon-specific prodrug4• Tetrasaccharide substrates of heparanase by glycosylation of disaccharides5• Synthetic heparin oligosaccharide microarrays for analysis of heparin-protein interactions6• Dexamethasone 21-sulfate sodium for use as a colon-specific prodrug7
Melting point	~85 °C

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

761-01-3

MDL number

MFCD00043315

PubChem substance

24888264

Beilstein registry

3993165

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Sulfur trioxide triethylamine complex used for?

Sulfur trioxide triethylamine complex is used as a reactant in organic synthesis, notably for preparing anticoagulants, anticancer agents, and specialised prodrugs.

What is the CAS number and formula for Sulfur trioxide triethylamine complex?

The CAS number is 761-01-3 and the linear formula is (CH3CH2)3N · SO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product at a technical grade with an assay of ≥95% on a sulfur basis (ICP). We do not represent this product as USP, BP, or EP grade.

How should Sulfur trioxide triethylamine complex be handled safely?

This compound causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, must be used. Handle in a well-ventilated area.