4-Methylumbelliferyl palmitate
4-Methylumbelliferyl palmitate (CAS 17695-48-6; C26H38O4) is a lipid-based fluorescent enzyme substrate with a molecular weight of 414.58 g/mol. It is primarily utilised as a fluorogenic substrate for detecting acid lipase activity in human leukocytes. This compound serves as a valuable tool in biochemical research, particularly in studies involving lipid metabolism and enzyme kinetics. Its fluorescence properties allow for sensitive detection and quantification of enzymatic activity.
- IUPAC
- Palmitic acid 4-methylumbelliferyl ester
- Synonyms
- Palmitic acid 4-methylumbelliferyl ester
Fluorogenic Substrate for Acid Lipase
4-Methylumbelliferyl palmitate functions as a specific fluorogenic substrate for assaying acid lipase activity. This is particularly relevant for the analysis of enzymes in human leukocytes, providing a sensitive method for activity determination.
Biochemical Research
This compound is employed in various biochemical research applications, including the study of lipid hydrolysis and enzyme kinetics. Its fluorescent properties enable precise measurements in biological samples.
Enzyme Activity Detection
As a fluorescent probe, it allows for the detection and quantification of esterase and lipase activities. Upon enzymatic cleavage, it releases 4-methylumbelliferone, which exhibits fluorescence, enabling sensitive detection.
| Molecular weight | 414.58 |
|---|---|
| Empirical formula | C26H38O4 |
| Storage temperature | −20°C |
| Application | Fluorogenic substrate for acid lipase in human leukocytes.1 |
| Melting point | 77 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 360 nm; λem 449 nm in 0.1 M phosphate pH 8.0 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylumbelliferyl palmitate used for?
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4-Methylumbelliferyl palmitate is used as a fluorogenic substrate for acid lipase in human leukocytes and for general biochemical research involving lipid hydrolysis and enzyme kinetics.
What is the CAS number and chemical formula for 4-Methylumbelliferyl palmitate?
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The CAS number is 17695-48-6, and the empirical formula is C26H38O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylumbelliferyl palmitate as a research chemical. The specific assay and purity details are available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for 4-Methylumbelliferyl palmitate?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling this chemical. It has a WGK Germany rating of 3, indicating it is hazardous to water.
How is 4-Methylumbelliferyl palmitate packed and shipped?
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4-Methylumbelliferyl palmitate is typically stored at -20°C. It is packed and exported by Tech Serve Solutions according to international shipping regulations for fine chemicals.
How can I request a quote or sample for 4-Methylumbelliferyl palmitate?
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To request a quote or a sample of 4-Methylumbelliferyl palmitate, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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