4-Methylumbelliferyl sulfate potassium salt
4-Methylumbelliferyl sulfate potassium salt (CAS: 15220-11-8), with the molecular formula C10H7KO6S and a molecular weight of 294.32 g/mol, is a vital fluorescent enzyme substrate. It is widely employed in biochemical research and diagnostics for the detection and quantification of enzymatic activity, particularly sulfatases. This compound offers a reliable and sensitive method for monitoring biological processes involving sulfate hydrolysis, producing a fluorescent product upon cleavage.
- IUPAC
- Potassium 4-methylumbelliferyl sulfate

Enzyme Activity Assays
Utilised as a fluorogenic substrate to detect and quantify the activity of sulfatase enzymes. Upon enzymatic hydrolysis, it releases 4-methylumbelliferone, which fluoresces under UV light.
Biochemical Research
Serves as a tool in molecular biology and biochemistry laboratories for studying enzyme kinetics and mechanisms. Its fluorescence allows for real-time monitoring of enzyme activity in various biological samples.
Diagnostic Kits
Incorporated into diagnostic kits for detecting specific enzyme deficiencies or activities relevant to certain medical conditions, leveraging its reliable fluorescent signal.
Cellular Imaging
Can be used in cell-based assays to visualise and measure sulfatase activity within living cells, providing insights into cellular processes and drug effects.
| Molecular weight | 294.32 |
|---|---|
| Empirical formula | C10H7KO6S |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 334 nm; λem 370 nm (pH 10.4)λex 360 nm; λem 449 nm (Reaction products) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylumbelliferyl sulfate potassium salt used for?
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It is primarily used as a fluorogenic substrate for assaying sulfatase enzyme activity in biochemical research and diagnostic applications. It produces a fluorescent signal upon enzymatic hydrolysis.
What is the CAS number and chemical formula for 4-Methylumbelliferyl sulfate potassium salt?
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The CAS number is 15220-11-8, and the chemical formula is C10H7KO6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Methylumbelliferyl sulfate potassium salt be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
How is this product shipped?
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This product is typically stored at -20°C. It is carefully packaged and exported by Tech Serve Solutions, adhering to all necessary regulations for chemical transport.
How can I request a sample or a quote for 4-Methylumbelliferyl sulfate potassium salt?
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Please contact our sales team via the website or email to request a sample or a personalised quote for 4-Methylumbelliferyl sulfate potassium salt.
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