4-Methylumbelliferyl α-D-mannopyranoside
4-Methylumbelliferyl α-D-mannopyranoside (CAS 28541-83-5) is a fluorescent substrate with the molecular formula C16H18O8 and a molecular weight of 338.31 g/mol. This compound is primarily utilised in biochemical research for the detection and quantification of alpha-mannosidase enzyme activity. Its fluorescence properties make it valuable for sensitive assays in molecular biology and glycobiology studies, facilitating the analysis of post-translational modifications.
Enzyme Activity Assays
Used as a fluorogenic substrate for the determination of alpha-mannosidase activity. The hydrolysis of this compound by the enzyme releases 4-methylumbelliferone, which exhibits fluorescence, allowing for sensitive detection and quantification.
Glycobiology Research
Facilitates studies in glycobiology by enabling the investigation of mannose-containing glycoconjugates and related enzymatic pathways. It aids in understanding carbohydrate structures and their biological roles.
Biochemical Research Tool
Serves as a valuable reagent in general biochemical research for probing enzyme kinetics and specificity, particularly for glycosidases. Its fluorescent nature allows for real-time monitoring of enzymatic reactions.
Post-Translational Modification Studies
Applicable in the study of post-translational modifications of proteins, specifically those involving glycosylation pathways that are dependent on alpha-mannosidase activity.
| Molecular weight | 338.31 |
|---|---|
| Empirical formula | C16H18O8 |
| Assay | ≥97% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|---|
| Fluorescence | λex 350 nm; λem 375 nm (pH 7.0)λex 360 nm; λem 449 nm (Reaction product) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylumbelliferyl α-D-mannopyranoside used for?
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4-Methylumbelliferyl α-D-mannopyranoside is primarily used as a fluorescent substrate for the assay of alpha-mannosidase enzyme activity in biochemical and glycobiology research.
What are the CAS number and formula for 4-Methylumbelliferyl α-D-mannopyranoside?
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The CAS number is 28541-83-5 and the empirical formula is C16H18O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylumbelliferyl α-D-mannopyranoside with a purity of ≥97% (HPLC), designated as PREMIUM quality. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 4-Methylumbelliferyl α-D-mannopyranoside be handled?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The substance has a WGK Germany classification of 3, indicating it is hazardous to water.
How is this chemical packed, shipped, and exported?
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This chemical is stored at -20°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote for 4-Methylumbelliferyl α-D-mannopyranoside?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through the website or by phone. We are happy to assist with your research needs.
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