4-(Fluorosulfonyl)benzoic acid
4-(Fluorosulfonyl)benzoic acid (CAS: 455-26-5) is a fluorinated organic building block with the molecular formula FSO2C6H4CO2H and a molecular weight of 204.18. This compound serves as a valuable reagent in chemical synthesis, particularly for introducing fluorosulfonyl functionalities. Its primary documented application involves its use as an affinity label for specific enzyme classes.
Affinity Labeling
4-(Fluorosulfonyl)benzoic acid has been employed as an affinity label for dimeric pig lung pi class glutathione S-transferase. This application highlights its utility in biochemical research for studying enzyme-protein interactions.
Organic Synthesis Reagent
As a functionalised benzoic acid derivative containing a reactive fluorosulfonyl group, it acts as a versatile building block in organic synthesis. It can be utilised in the preparation of various complex molecules and fluorinated compounds.
Fluorinated Compound Synthesis
This compound is a key intermediate for the synthesis of more complex organic molecules incorporating fluorine atoms. Fluorinated organic compounds often exhibit unique properties relevant to pharmaceuticals and materials science.
| Molecular weight | 204.18 |
|---|---|
| Linear formula | FSO2C6H4CO2H |
| Assay | 95% |
| Application | 4-(Fluorosulfonyl)benzoic acid was used as an affinity label of dimeric pig lung pi class glutathione S-transferase1. |
| Melting point | 272-273 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Fluorosulfonyl)benzoic acid primarily used for?
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4-(Fluorosulfonyl)benzoic acid is primarily used as an affinity label in biochemical studies, for instance, of dimeric pig lung pi class glutathione S-transferase, and as a versatile building block in organic synthesis, particularly for introducing fluorosulfonyl groups and synthesising fluorinated compounds.
What is the CAS number and chemical formula for 4-(Fluorosulfonyl)benzoic acid?
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The CAS number for 4-(Fluorosulfonyl)benzoic acid is 455-26-5, and its chemical formula is FSO2C6H4CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Fluorosulfonyl)benzoic acid with an assay of 95%. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade.
How should 4-(Fluorosulfonyl)benzoic acid be handled safely?
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4-(Fluorosulfonyl)benzoic acid is classified as Dangerous. It causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, a face shield, and chemical-resistant gloves, is essential. Always consult the Safety Data Sheet (SDS) before handling. Ensure adequate ventilation and use a suitable respirator if airborne exposure is possible.
Is 4-(Fluorosulfonyl)benzoic acid exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-(Fluorosulfonyl)benzoic acid.
How can I request a quote or sample for 4-(Fluorosulfonyl)benzoic acid?
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To request a quote or sample for 4-(Fluorosulfonyl)benzoic acid, please use the contact form on our website or contact our sales team directly.
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