4-(Fmoc-aminomethyl)benzoic acid

CAS 164470-64-8C23H19NO4Chemical Synthesis

4-(Fmoc-aminomethyl)benzoic acid (CAS: 164470-64-8; Formula: C23H19NO4; MW: 373.40) is a protected aromatic amino acid derivative vital for solid-phase peptide synthesis. Its structure incorporates the Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, allowing for controlled deprotection during chain elongation. This compound serves as a key building block in the construction of complex peptides and peptidomimetics, finding application in chemical biology and the synthesis of unnatural amino acid derivatives. TSS supplies this high-purity reagent for research and development purposes.

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4-(Fmoc-aminomethyl)benzoic acid (C23H19NO4) — chemical structure, CAS 164470-64-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Aromatic Amino AcidsChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

Serves as a crucial building block in solid-phase peptide synthesis (SPPS) and solution-phase peptide synthesis, enabling the introduction of a protected aminomethyl benzoic acid residue into peptide chains.

Chemical Biology

Utilised in the creation of modified peptides for biochemical studies, probe development, and investigating protein-protein interactions, offering a unique structural motif.

Unnatural Amino Acid Derivatives

A key intermediate in the synthesis of non-proteinogenic amino acids, expanding the chemical space for drug discovery and materials science.

Organic Synthesis

Employed as a versatile reagent in complex organic synthesis pathways requiring precisely functionalised aromatic moieties.

02 /Properties

Molecular weight	373.40
Empirical formula	C23H19NO4
Assay	≥98.0%
Storage temperature	2-8°C
Melting point	224-228 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

164470-64-8

MDL number

MFCD01074693

Beilstein registry

7391207

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-(Fmoc-aminomethyl)benzoic acid used for?

4-(Fmoc-aminomethyl)benzoic acid is primarily used as a building block in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), and in the creation of unnatural amino acid derivatives for chemical biology and organic synthesis applications.

What is the CAS number and molecular formula for 4-(Fmoc-aminomethyl)benzoic acid?

The CAS number is 164470-64-8 and the molecular formula is C23H19NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-(Fmoc-aminomethyl)benzoic acid with a purity of ≥98.0%. We do not represent this product as USP, BP, or EP grade.

How should 4-(Fmoc-aminomethyl)benzoic acid be handled and stored?

Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.

Is 4-(Fmoc-aminomethyl)benzoic acid a controlled substance?

The provided data does not indicate that 4-(Fmoc-aminomethyl)benzoic acid is a controlled substance.

How is 4-(Fmoc-aminomethyl)benzoic acid packed and exported?

Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all necessary shipping regulations for safe and timely delivery.