4-(Fmoc-amino)piperidine hydrochloride
4-(Fmoc-amino)piperidine hydrochloride (CAS: 221352-86-9), a key piperidine derivative with the molecular formula C20H22N2O2 · HCl and a molecular weight of 358.86 g/mol, serves as a valuable building block. Its primary application lies in chemical synthesis, particularly as a combinatorial reactant in the development of ergopeptides with specific affinities for dopamine receptors. This compound is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- N(4)-Fmoc-4-piperidinamine hydrochloride

Synthesis of Dopamine Receptor Ligands
Utilised as a combinatorial reactant for the synthesis of ergopeptides. These molecules are designed to exhibit high affinities for dopamine receptors, making them significant in neurological research.
Piperidine Derivative in Organic Synthesis
As a functionalised piperidine, it is a versatile building block in complex organic synthesis. It allows for the introduction of the piperidine moiety and the Fmoc-protected amine functionality into larger molecular structures.
Development of Pharmaceutical Intermediates
The compound's structure makes it suitable for incorporation into potential pharmaceutical intermediates. Its specific functional groups can be further elaborated in multi-step synthetic pathways.
| Molecular weight | 358.86 |
|---|---|
| Empirical formula | C20H22N2O2 · HCl |
| Assay | ≥95.0% |
| Application | Combinatorial reactant for ergopeptides with high affinities for dopamine receptors1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Fmoc-amino)piperidine hydrochloride used for?
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4-(Fmoc-amino)piperidine hydrochloride is primarily used as a combinatorial reactant in the synthesis of ergopeptides designed to have high affinities for dopamine receptors. It also serves as a versatile building block in general organic synthesis and for developing pharmaceutical intermediates.
What are the CAS number and formula for 4-(Fmoc-amino)piperidine hydrochloride?
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The CAS number for 4-(Fmoc-amino)piperidine hydrochloride is 221352-86-9, and its molecular formula is C20H22N2O2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Fmoc-amino)piperidine hydrochloride with an assay of ≥95.0%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for this chemical?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It carries a WGK Germany rating of 3, indicating a significant hazard to water.
How is 4-(Fmoc-amino)piperidine hydrochloride packed and shipped?
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Tech Serve Solutions expertly packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant transport regulations.
How can I request a sample or quote for 4-(Fmoc-amino)piperidine hydrochloride?
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To request a sample or a quotation for 4-(Fmoc-amino)piperidine hydrochloride, please contact our sales department via the website or direct email, providing your specific requirements.
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