4-(Ethoxycarbonyl)phenylzinc bromide solution
4-(Ethoxycarbonyl)phenylzinc bromide solution (CAS: 131379-15-2) is an organozinc halide supplied by Tech Serve Solutions. With the linear formula C₂H₅O₂CC₆H₄ZnBr and a molecular weight of 294.46 g/mol, this reagent is provided as a 0.5 M solution in THF, often containing 1-3% inorganic chloride impurities. It is primarily utilised as a versatile building block in organic synthesis, particularly for cross-coupling reactions.
Cross-Coupling Reactions
This organozinc bromide serves as a valuable nucleophilic coupling partner in transition metal-catalysed reactions, such as Negishi couplings. It enables the formation of new carbon-carbon bonds by reacting with aryl or vinyl halides.
Synthesis of Complex Molecules
The reagent is instrumental in the construction of complex organic frameworks, including pharmaceuticals and advanced materials. Its functional group tolerance allows for the introduction of the ethoxycarbonylphenyl moiety into various molecular structures.
Preparation of Organometallic Intermediates
It acts as a precursor for generating other organozinc species or can be directly employed in reactions requiring a reactive aryl zinc reagent. This facilitates diverse synthetic transformations.
| Molecular weight | 294.46 |
|---|---|
| Linear formula | C2H5O2CC6H4ZnBr |
| Boiling point | 65 °C |
| Density | 1.023 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
| Impurities tested | 1-3% inorganic chloride |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Ethoxycarbonyl)phenylzinc bromide solution used for?
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4-(Ethoxycarbonyl)phenylzinc bromide solution is primarily used in organic synthesis for cross-coupling reactions, such as Negishi couplings, and for the synthesis of complex molecules by forming new carbon-carbon bonds.
What are the CAS number and formula for 4-(Ethoxycarbonyl)phenylzinc bromide solution?
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The CAS number is 131379-15-2 and the linear formula is C₂H₅O₂CC₆H₄ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF, with 1-3% inorganic chloride impurities. TSS does not represent this product as USP/BP/EP grade.
What are the main safety hazards associated with this chemical?
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This solution is highly flammable (H225) and corrosive (H314), causing severe skin burns and eye damage. It may also cause respiratory irritation (H335) and is suspected of causing cancer (H351). It may form explosive peroxides.
How is this chemical shipped and exported?
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This chemical is classified under UN 2920, Class 3 (flammable liquids) with a subsidiary risk of Class 8 (corrosive), Packing Group II. Shipments and exports are handled in compliance with relevant dangerous goods regulations.
How can I request a sample or quote?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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