4-Fluorophenylboronic acid MIDA ester
4-Fluorophenylboronic acid MIDA ester (CAS 1257641-06-7) is an organoboron compound with the molecular formula C11H11BFNO4 and a molecular weight of 251.02 g/mol. It is a derivative of boronic acid, stabilised in a MIDA ester form, making it a valuable reagent in organic synthesis. This compound is particularly useful in Suzuki cross-coupling reactions, enabling the formation of carbon-carbon bonds. Available at 97% purity, it serves as a reliable building block for complex molecule construction in research and development.
- IUPAC
- 2-(4-Fluorophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione
- Synonyms
- 2-(4-Fluorophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione
Suzuki Cross-Coupling Reactions
4-Fluorophenylboronic acid MIDA ester is employed as a key coupling partner in Suzuki-Miyaura cross-coupling reactions. Its MIDA ester form offers enhanced stability and handling properties compared to free boronic acids.
Synthesis of Biologically Active Molecules
This reagent serves as a crucial intermediate in the synthesis of pharmaceuticals and agrochemicals. The 4-fluorophenyl moiety is a common structural feature in many active pharmaceutical ingredients.
Material Science Applications
It can be utilised in the development of new organic materials, such as conjugated polymers and organic light-emitting diodes (OLEDs), where precise control over molecular structure is essential.
| Molecular weight | 251.02 |
|---|---|
| Empirical formula | C11H11BFNO4 |
| Assay | 97% |
| Application | Suzuki Cross-Coupling with MIDA Boronates |
| Melting point | 231-236 °C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorophenylboronic acid MIDA ester used for?
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4-Fluorophenylboronic acid MIDA ester is primarily used in Suzuki cross-coupling reactions for the synthesis of complex organic molecules, including pharmaceuticals and advanced materials.
What is the CAS number and formula for 4-Fluorophenylboronic acid MIDA ester?
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The CAS number is 1257641-06-7, and the empirical formula (Hill notation) is C11H11BFNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorophenylboronic acid MIDA ester with a minimum assay of 97%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should 4-Fluorophenylboronic acid MIDA ester be handled?
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This compound is classified as harmful if swallowed (H302). When handling, it is recommended to wear eye shields, gloves, and a dust mask type N95 (US). Avoid ingestion and dust formation.
Is 4-Fluorophenylboronic acid MIDA ester a controlled substance?
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The provided data does not indicate that 4-Fluorophenylboronic acid MIDA ester is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions offers this chemical in various pack sizes suitable for laboratory and industrial use. We are experienced global exporters adhering to all relevant shipping and customs regulations.
How can I request a sample or a quote for 4-Fluorophenylboronic acid MIDA ester?
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To request a sample or a quote, please contact our sales team through the website or by direct enquiry, providing your specific requirements and delivery details.
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