4-Fluorophenylacetonitrile
4-Fluorophenylacetonitrile (CAS: 459-22-3) is an organic compound with the formula FC6H4CH2CN and a molecular weight of 135.14 g/mol. This fluorinated aromatic nitrile serves as a key building block in organic synthesis. It is widely employed in the development of pharmaceuticals, agrochemicals, and advanced materials, owing to the unique properties imparted by the fluorine atom and the reactive nitrile group. TSS offers this compound with a minimum assay of 99%.
- IUPAC
- 4-Fluorobenzyl cyanide
- Synonyms
- 4-Fluorobenzyl cyanide
Pharmaceutical Intermediate
Used in the synthesis of various active pharmaceutical ingredients (APIs), contributing to the development of novel therapeutics.
Agrochemical Synthesis
Serves as a precursor for creating advanced crop protection agents and pesticides, enhancing agricultural efficiency.
Material Science
Incorporated into the synthesis of specialised polymers and organic electronic materials, leveraging its unique structural and electronic properties.
Organic Synthesis Reagent
A versatile building block in general organic chemistry for introducing the 4-fluorobenzyl moiety into complex molecules.
| Molecular weight | 135.14 |
|---|---|
| Linear formula | FC6H4CH2CN |
| Assay | 99% |
| Boiling point | 119-120 °C/18 mmHg(lit.) |
| Density | 1.126 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5002(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Transport (UN / ADR) | UN 3276 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorophenylacetonitrile used for?
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4-Fluorophenylacetonitrile is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, and as a versatile building block in organic synthesis.
What are the CAS number and formula for 4-Fluorophenylacetonitrile?
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The CAS number is 459-22-3 and the molecular formula is FC6H4CH2CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorophenylacetonitrile with a minimum assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 4-Fluorophenylacetonitrile be handled safely?
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4-Fluorophenylacetonitrile is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation. It may also cause respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.
How is 4-Fluorophenylacetonitrile packed and exported?
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4-Fluorophenylacetonitrile is packed according to international shipping regulations for hazardous materials (UN 3276, Class 6.1, PGIII) and is available for global export.
How can I request a quote or sample?
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To request a quote or a sample of 4-Fluorophenylacetonitrile, please contact our sales team through the TSS website or by phone.
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