(3αR,7αR)-1,3-Dimethyl-2-(1-piperidinyl)octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide
(3αR,7αR)-1,3-Dimethyl-2-(1-piperidinyl)octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide (CAS: 161390-52-9) is a chiral organocatalyst with a molecular weight of 271.34 g/mol. It is recognised for its role in asymmetric synthesis, particularly in the enantioselective allylation of aldehydes. Supplied by Tech Serve Solutions with an assay of ≥98.0% (GC), this compound is valuable for researchers and chemists engaged in complex organic synthesis.
- Synonyms
- 3,2-benzodiazaphosphole 2-oxide
Asymmetric Allylation of Aldehydes
This compound serves as a chiral Lewis base organocatalyst. It facilitates the enantioselective allylation of aldehydes, a key transformation in the synthesis of chiral molecules. Research indicates its efficacy in achieving high levels of stereocontrol.
Chiral Ligand in Organic Synthesis
As a chiral ligand, it can be employed in various catalytic asymmetric reactions. Its unique structural features enable the induction of chirality in organic transformations, contributing to the development of stereospecific synthetic routes.
Catalyst for Asymmetric Synthesis
It is utilised in the field of asymmetric synthesis, enabling the creation of enantiomerically enriched compounds. This is crucial for pharmaceuticals and fine chemicals where specific stereoisomers are required.
| Molecular weight | 271.34 |
|---|---|
| Empirical formula | C13H26N3OP |
| Assay | ≥98.0% (GC) |
| Optical activity | [α]/D -90.5±3°, c = 1.15 in chloroform |
| Application | Organocatalyst: Asymmetric Allylation of Aldehydes with Chiral Lewis Bases1, Review2 |
| Melting point | 108-112 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3αR,7αR)-1,3-Dimethyl-2-(1-piperidinyl)octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide used for?
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This compound is primarily used as a chiral organocatalyst in asymmetric synthesis, notably for the enantioselective allylation of aldehydes.
What is the CAS number and empirical formula?
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The CAS number is 161390-52-9 and the empirical formula is C13H26N3OP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥98.0% (GC). It is supplied for research and development purposes and is not represented as USP, BP, EP or pharmacopoeia grade.
What are the safety and handling recommendations?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. Refer to the safety data sheet for detailed handling information. The compound is classified with WGK Germany 3.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packaging and shipping details are available upon request and comply with international regulations for the export of chemical products.
How can I request a sample or a quote?
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To request a sample or obtain a quote, please contact the Tech Serve Solutions sales team through our website or direct contact details, specifying the product CAS number 161390-52-9.
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