(4-(1-Piperidinylmethyl)phenyl)magnesium bromide solution
(4-(1-Piperidinylmethyl)phenyl)magnesium bromide solution (CAS 480424-83-7) is an organometallic reagent with the linear formula C6H4CH2NC5H10MgBr and a molecular weight of 278.47 g/mol. Supplied as a 0.25 M solution in THF, it exhibits a boiling point of 65 °C and a density of 0.924 g/mL at 25 °C. This compound is primarily utilised in organic synthesis for introducing aryl fragments into molecules, particularly in reactions requiring nucleophilic addition or substitution.
Organic Synthesis
As a Grignard reagent, it is employed in carbon-carbon bond formation, enabling the synthesis of complex organic molecules. It serves as a valuable building block in the preparation of pharmaceuticals and advanced materials.
Pharmaceutical Intermediates
This reagent is instrumental in the synthesis pathways of various active pharmaceutical ingredients (APIs) and drug candidates. Its specific structure allows for targeted functionalisation in complex molecular architectures.
Research and Development
Utilised in academic and industrial research settings to explore new synthetic methodologies and develop novel chemical entities. Its reactivity profile makes it a key component in exploring diverse chemical transformations.
| Molecular weight | 278.47 |
|---|---|
| Linear formula | C6H4CH2NC5H10MgBr |
| Boiling point | 65 °C |
| Density | 0.924 g/mL at 25 °C |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (4-(1-Piperidinylmethyl)phenyl)magnesium bromide solution used for?
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(4-(1-Piperidinylmethyl)phenyl)magnesium bromide solution is primarily used in organic synthesis for carbon-carbon bond formation and as a key building block in the preparation of pharmaceutical intermediates and novel chemical entities.
What are the CAS number and formula for this compound?
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The CAS number is 480424-83-7 and the linear formula is C6H4CH2NC5H10MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a 0.25 M solution in THF. We do not represent this product as USP, BP, or EP grade.
How should (4-(1-Piperidinylmethyl)phenyl)magnesium bromide solution be handled?
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This compound is highly flammable and corrosive. It reacts violently with water and may form explosive peroxides. Handle with extreme care in a well-ventilated area, away from ignition sources, and use appropriate personal protective equipment. Refer to the Safety Data Sheet for detailed handling instructions.
How is this product packed, shipped, and exported?
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This product is supplied in suitable containers for safe transport, adhering to UN 2924 (8(3) / PGII) regulations. Tech Serve Solutions is experienced in global exporting of fine chemicals.
How can I request a sample or quote?
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Please contact our sales team or use the online enquiry form to request a sample or a quotation for (4-(1-Piperidinylmethyl)phenyl)magnesium bromide solution.
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