(3aS-cis)-(−)-3,3a,8,8a-Tetrahydro-2H-indeno[1,2-d]oxazol-2-one
(3aS-cis)-(−)-3,3a,8,8a-Tetrahydro-2H-indeno[1,2-d]oxazol-2-one (CAS: 135969-64-1) is a chiral oxazolidinone derivative with the molecular formula C10H9NO2 and a molecular weight of 175.18 g/mol. It is a valuable building block in asymmetric synthesis, particularly for the preparation of enantiomerically enriched compounds. Its defined stereochemistry makes it instrumental in stereoselective chemical transformations.
- Synonyms
- 8a-Tetrahydro-2H-indeno[1,2-d]oxazol-2-one
![(3aS-cis)-(−)-3,3a,8,8a-Tetrahydro-2H-indeno[1,2-d]oxazol-2-one (C10H9NO2) — chemical structure, CAS 135969-64-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F135969-64-1.png&w=3840&q=75)
Chiral Auxiliary in Asymmetric Synthesis
This compound serves as an effective chiral auxiliary, enabling the stereoselective synthesis of complex organic molecules. It can be incorporated into a substrate and later removed, imparting chirality to the target molecule.
Building Block for Pharmaceutical Intermediates
Its unique indeno-oxazolidinone structure makes it a useful precursor for synthesizing chiral pharmaceutical intermediates. The defined stereocentres are crucial for developing stereochemically pure active pharmaceutical ingredients (APIs).
Reagent in Stereoselective Reactions
Used in various stereoselective reactions to control the formation of new chiral centres. Its application helps achieve high enantiomeric excess (ee) in synthetic pathways.
| Molecular weight | 175.18 |
|---|---|
| Empirical formula | C10H9NO2 |
| Assay | 98% |
| Optical activity | [α]22/D −76°, c = 0.65 in ethyl acetate |
| Optical purity | ee: 99% (HPLC) |
| Melting point | 203-209 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3aS-cis)-(−)-3,3a,8,8a-Tetrahydro-2H-indeno[1,2-d]oxazol-2-one used for?
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This compound is primarily used as a chiral auxiliary in asymmetric synthesis and as a building block for stereoselective chemical reactions, including the preparation of pharmaceutical intermediates.
What is the CAS number and molecular formula for this product?
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The CAS number is 135969-64-1, and the molecular formula is C10H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum assay of 98%. It is provided as a research-grade chemical and is not represented as USP, BP, or EP grade.
How should (3aS-cis)-(−)-3,3a,8,8a-Tetrahydro-2H-indeno[1,2-d]oxazol-2-one be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling guidelines.
Is this product suitable for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, including this compound.
How can I request a sample or quote?
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To request a sample or a quote for (3aS-cis)-(−)-3,3a,8,8a-Tetrahydro-2H-indeno[1,2-d]oxazol-2-one, please contact our sales team through the website or by phone.
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