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(3aS,4R,5S,6aR)-(+)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one

CAS 76704-05-75SChemical Synthesis

(3aS,4R,5S,6aR)-(+)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one (CAS 76704-05-7), with the molecular formula C8H12O4 and a molecular weight of 172.18 g/mol, is a chiral lactone. This compound is a valuable building block in organic synthesis, particularly for the construction of complex molecules. It serves as a key intermediate in asymmetric synthesis and is supplied by TSS at a minimum purity of 98%.

IUPAC
(+)-Corey lactone
Synonyms
(+)-Corey lactone(3aS,4R,5S,6aR)-(+)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
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(3aS,4R,5S,6aR)-(+)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one (5S) — chemical structure, CAS 76704-05-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksLactonesOrganic Building Blocks
01 /Applications

Asymmetric Synthesis

This chiral lactone is frequently employed as a stereodefined building block in asymmetric synthesis. Its defined stereochemistry allows for the precise construction of chiral centres in target molecules.

Organic Synthesis Intermediate

As a versatile organic building block, it is used in multi-step synthetic routes for the preparation of various organic compounds. Its furanone core can be readily functionalised.

Chiral Pool Synthesis

The compound belongs to the category of chiral pool materials, which are naturally occurring or readily available chiral compounds used as starting materials in enantioselective synthesis.

02 /Properties
Molecular weight172.18
Empirical formulaC8H12O4
Assay98%
Optical activity[α]20/D +44°, c = 2.3 in methanol
Melting point114-118 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
76704-05-7
MDL number
MFCD00274285
PubChem substance
24868771
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (3aS,4R,5S,6aR)-(+)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one used for?

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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic synthesis.

What is the CAS number and molecular formula for this compound?

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The CAS number is 76704-05-7, and the molecular formula is C8H12O4.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this chemical with an assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.

What are the safety and handling considerations?

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Appropriate personal protective equipment, including eyeshields and gloves, is recommended. If dust is generated, use a type N95 (US) or type P1 (EN143) respirator filter. This compound is classified under WGK 2 in Germany, indicating it is hazardous to water.

How is this chemical shipped or exported?

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Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, handling all aspects of shipping and export.

How can I request a sample or quote?

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Please contact our sales team directly via the website or email to request a sample or a quotation for this product.

Need (3aS,4R,5S,6aR)-(+)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one in a specific grade or volume?