(3aR,8aR)-4,4,8,8-tetrakis(3,5-di-tert-butylphenyl)-2,2-diethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine
(3aR,8aR)-4,4,8,8-tetrakis(3,5-di-tert-butylphenyl)-2,2-diethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine (CAS 1241684-27-4) is a complex organophosphorus compound with the molecular formula C71H101O4P. This chemical, weighing 1049.53 g/mol, is primarily utilised as a reactant in the preparation of potent and selective small molecule inhibitors for specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
- Synonyms
- 8,8-tetrakis(3,5-di-tert-butylphenyl)-2,2-diethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine1241684-27-4C71H101O4P
![(3aR,8aR)-4,4,8,8-tetrakis(3,5-di-tert-butylphenyl)-2,2-diethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine (C71H101O4P) — chemical structure, CAS 1241684-27-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1241684-27-4.png&w=3840&q=75)
Synthesis of Kinase Inhibitors
This compound serves as a crucial reactant in the synthesis of small molecule inhibitors targeting Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk). These inhibitors are designed for high potency and isoform selectivity.
Asymmetric Synthesis
As a chiral reagent, it finds application in asymmetric synthesis, contributing to the stereoselective construction of complex organic molecules, which is vital in pharmaceutical research and development.
Chemical Synthesis Reagent
Its unique structure makes it a valuable reagent in broader chemical synthesis, enabling the creation of novel compounds and facilitating complex organic transformations.
| Molecular weight | 1049.53 |
|---|---|
| Empirical formula | C71H101O4P |
| Assay | ≥94% |
| Storage temperature | −20°C |
| Application | Reactant for:• Preparation of potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk)1 |
| Melting point | 187-193 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3aR,8aR)-4,4,8,8-tetrakis(3,5-di-tert-butylphenyl)-2,2-diethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine used for?
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This compound is used as a reactant for the preparation of potent and selective small molecule inhibitors of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
What is the CAS number and formula for this chemical?
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The CAS number is 1241684-27-4 and the empirical formula (Hill notation) is C71H101O4P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥94%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
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This chemical has a GHS classification of Water Hazard Class 3 (WGK 3), indicating it is hazardous to the aquatic environment. It should be handled with appropriate personal protective equipment in a well-ventilated area, and precautions should be taken to prevent its release into the environment. Storage should be at -20°C.
How is this product packed, shipped, and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. This product is packed, shipped, and exported in accordance with international regulations for hazardous materials, ensuring safe and compliant transit.
How can I request a sample or quote for this product?
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To request a sample or a quotation for (3aR,8aR)-4,4,8,8-tetrakis(3,5-di-tert-butylphenyl)-2,2-diethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine, please contact our sales team through the website or by phone.
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