(3aR,4S,5R,6aS)-(−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
(−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one (CAS 32233-40-2) is a chiral lactone with the molecular formula C8H12O4 and a molecular weight of 172.18 g/mol. This compound is frequently employed as a key building block in asymmetric synthesis and chemical research. Its specific stereochemistry makes it valuable for constructing complex molecules where precise spatial arrangement is critical, particularly in the development of novel pharmaceuticals and fine chemicals.
- IUPAC
- (−)-Corey lactone
- Synonyms
- (−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydrocyclopenta[b]furan-2(3H)-one(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one32233-40-2C8H12O4Corey Lactone
![(3aR,4S,5R,6aS)-(−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one (5R) — chemical structure, CAS 32233-40-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F32233-40-2.png&w=3840&q=75)
Chiral Building Block in Asymmetric Synthesis
This lactone serves as a crucial chiral synthon for the enantioselective synthesis of complex organic molecules. Its defined stereocenters facilitate the introduction of chirality in target compounds.
Intermediate for Pharmaceutical Development
The unique structure of (3aR,4S,5R,6aS)-(−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one makes it a valuable intermediate in the synthesis pathways for various potential drug candidates.
Organic Synthesis Reagent
Utilised in academic and industrial research laboratories for diverse organic transformations, contributing to the advancement of synthetic methodologies.
| Molecular weight | 172.18 |
|---|---|
| Empirical formula | C8H12O4 |
| Assay | 98% |
| Optical activity | [α]20/D −44°, c = 1.4 in methanol |
| Melting point | 117-119 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3aR,4S,5R,6aS)-(−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic synthesis, particularly for pharmaceutical development.
What are the CAS number and molecular formula?
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The CAS number is 32233-40-2, and the molecular formula is C8H12O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance is classified with WGK 3 in Germany, indicating a high hazard to water.
How is this chemical shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, providing this product with appropriate packaging and documentation for international shipment.
How can I request a sample or quote?
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To request a sample or a quotation for (3aR,4S,5R,6aS)-(−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one, please contact our sales department through the website or by phone.
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