5-Methoxy-2-methylindole
5-Methoxy-2-methylindole (CAS: 1076-74-0), with the molecular formula C10H11NO and a molecular weight of 161.20 g/mol, is a key heterocyclic building block. It serves as a vital reactant in various organic synthesis pathways. Its applications are primarily focused on the preparation of complex organic molecules, including indolylquinoxalines and substituted indoles, through diverse chemical transformations. TSS offers this compound for research and development purposes.
- IUPAC
- NSC 63817
Synthesis of Indolylquinoxalines
5-Methoxy-2-methylindole acts as a reactant in condensation reactions for the preparation of indolylquinoxalines, contributing to the synthesis of novel heterocyclic compounds.
Reductive Alkylation of Indoles
This compound is utilised as a reactant in iridium-catalysed reductive alkylation processes, facilitating the introduction of alkyl groups onto indole structures.
Palladium-Catalysed Arylation
It participates in arylation reactions when catalysed by palladium acetate, enabling the formation of carbon-carbon bonds and the synthesis of arylated indole derivatives.
Enantioselective Friedel-Crafts Alkylation
5-Methoxy-2-methylindole is employed in enantioselective Friedel-Crafts alkylation reactions, allowing for the stereoselective synthesis of chiral indole derivatives.
Stereoselective Cyclopentannulation
The compound serves as a reactant in stereoselective [3+2] cyclopentannulation reactions, leading to the synthesis of cyclopentaindolones with controlled stereochemistry.
| Molecular weight | 161.20 |
|---|---|
| Empirical formula | C10H11NO |
| Assay | 99% |
| Application | reactant in preparation of indolylquinoxalines by condensation reactions1reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation2reactant in arylation reactions using a palladium acetate catalyst3reactant in enantioselective Friedel-Crafts alkylation4reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation5 |
| Melting point | 86-88 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methoxy-2-methylindole primarily used for?
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5-Methoxy-2-methylindole is primarily used as a building block in organic synthesis, particularly in the preparation of indolylquinoxalines, alkylindoles, and in enantioselective and stereoselective reactions like Friedel-Crafts alkylation and cyclopentannulation.
What are the CAS number and molecular formula for 5-Methoxy-2-methylindole?
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The CAS number for 5-Methoxy-2-methylindole is 1076-74-0, and its molecular formula is C10H11NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methoxy-2-methylindole with a minimum assay of 99%. This product is intended for laboratory and research use and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for 5-Methoxy-2-methylindole?
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5-Methoxy-2-methylindole is classified with GHS hazards. Please consult the Safety Data Sheet (SDS) for detailed information on hazards, handling, storage, and personal protective equipment. Users should exercise caution and adhere to standard laboratory safety protocols.
Is 5-Methoxy-2-methylindole a controlled substance?
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The provided data does not indicate that 5-Methoxy-2-methylindole (CAS: 1076-74-0) is a controlled substance.
How is 5-Methoxy-2-methylindole packed and exported?
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5-Methoxy-2-methylindole is carefully packed to ensure stability during transit. Tech Serve Solutions is a global supplier and exporter, adhering to all relevant shipping regulations for chemical products.
How can I request a sample or quote for 5-Methoxy-2-methylindole?
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To request a sample or a quote for 5-Methoxy-2-methylindole, please contact our sales department through the enquiry form on our website or by direct email, providing your contact details and the quantity required.
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