5-Methoxy-2-methyl-3-indoleacetic acid
5-Methoxy-2-methyl-3-indoleacetic acid (CAS: 2882-15-7), with the molecular formula C12H13NO3 and a molecular weight of 219.24 g/mol, is a valuable indole derivative. It serves as a key building block in organic synthesis, particularly for the preparation of various biologically active compounds. Its applications span the development of pharmaceutical agents, including antimalarials, anti-inflammatory drugs, and selective imaging agents.
- IUPAC
- N-Des(4-chlorobenzoyl)indomethacin,NSC 97026
Antimalarial Agents Synthesis
This compound is a reactant used in the synthesis of antimalarial agents, contributing to the development of new therapeutic strategies against malaria.
Anti-inflammatory Drug Development
It serves as a reactant for preparing indomethacin analogs with anti-inflammatory activity by inhibiting cyclooxygenase and lipoxygenase pathways.
Targeted Imaging Agents
Used as a reactant in the preparation of [123I]-indomethacin derivatives, these compounds are designed as selective imaging agents for COX-2.
Histone Deacetylase Inhibitors
5-Methoxy-2-methyl-3-indoleacetic acid is a reactant in the synthesis of histone deacetylase inhibitors, which are investigated for various therapeutic applications.
Adenosine Receptor Ligands
The compound is utilised in preparing substituted adenosine derivatives that act as ligands for the A2B adenosine receptor.
Prostaglandin Receptor Antagonists
It functions as a reactant in the development of prostaglandin D2 receptor antagonists.
| Molecular weight | 219.24 |
|---|---|
| Empirical formula | C12H13NO3 |
| Assay | 98% |
| Solubility | methanol: soluble |
| Application | • Reactant for preparation of antimalarial agents• Reactant for preparation of ndomethacin analogs as cyclooxygenase and lipoxygenase inhibitors with antiinflammatory activity• Reactant for preparation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents• Reactant for preparation of histone deacetylase inhibitors• Reactant for preparation of 2,N6,5′-substituted adenosine derivatives as ligands for A2B adenosine receptor• Reactant for preparation of prostaglandin D2 receptor antagonist |
| Melting point | 161-163 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methoxy-2-methyl-3-indoleacetic acid used for?
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5-Methoxy-2-methyl-3-indoleacetic acid is used as a reactant in the synthesis of various biologically active compounds, including antimalarial agents, anti-inflammatory drugs, targeted imaging agents, histone deacetylase inhibitors, adenosine receptor ligands, and prostaglandin D2 receptor antagonists.
What is the CAS number and molecular formula for this compound?
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The CAS number is 2882-15-7, and the molecular formula is C12H13NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methoxy-2-methyl-3-indoleacetic acid with an assay of 98%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling this chemical?
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Handling this chemical requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified under WGK Germany 3, indicating a high hazard level.
How is 5-Methoxy-2-methyl-3-indoleacetic acid packaged and shipped?
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Tech Serve Solutions expertly packages and exports fine chemicals, laboratory reagents, and pharmaceutical intermediates globally. Specific packaging details will be provided with your quotation.
How can I request a sample or quote for this product?
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To request a sample or a quotation for 5-Methoxy-2-methyl-3-indoleacetic acid, please contact our sales department via the website or by calling our customer service line.
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