5-Methoxy-2-benzimidazolethiol
5-Methoxy-2-benzimidazolethiol (CAS: 37052-78-1; C8H8N2OS; MW: 180.23) is a heterocyclic organic compound featuring a benzimidazole core with a methoxy group and a thiol substituent. This chemical serves as a versatile building block in organic synthesis. It is primarily utilised in the development of novel compounds and intermediates, particularly within the fields of medicinal chemistry and materials science, owing to its reactive functional groups.

Organic Synthesis Intermediate
Used as a precursor or intermediate in the synthesis of more complex organic molecules. Its functional groups allow for various chemical transformations.
Medicinal Chemistry Research
Employed in the development of potential pharmaceutical agents. The benzimidazole scaffold is a common motif in biologically active compounds.
Heterocyclic Chemistry
Serves as a valuable building block for constructing diverse heterocyclic systems. Useful in the exploration of novel chemical entities.
| Molecular weight | 180.23 |
|---|---|
| Empirical formula | C8H8N2OS |
| Assay | 99% |
| Melting point | 261-263 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methoxy-2-benzimidazolethiol used for?
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5-Methoxy-2-benzimidazolethiol is used as a building block in organic synthesis, particularly in medicinal chemistry and the development of heterocyclic compounds.
What are the CAS number and formula for 5-Methoxy-2-benzimidazolethiol?
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The CAS number for 5-Methoxy-2-benzimidazolethiol is 37052-78-1, and its empirical formula is C8H8N2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methoxy-2-benzimidazolethiol with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 5-Methoxy-2-benzimidazolethiol be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust, ensure adequate ventilation, and wash hands thoroughly after handling. Specific precautionary statements include P261 and P305 + P351 + P338.
Does Tech Serve Solutions export 5-Methoxy-2-benzimidazolethiol?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Methoxy-2-benzimidazolethiol.
How can I request a sample or quote for 5-Methoxy-2-benzimidazolethiol?
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To request a sample or quote, please contact our sales department via the website or direct inquiry, providing your contact details and the product CAS number (37052-78-1).
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