Methiothepin mesylate salt
Methiothepin mesylate salt (CAS 74611-28-2), with the molecular formula C20H24N2S2 · CH3SO3H and a molecular weight of 452.65, is supplied as a white solid. This compound functions primarily as a serotonin receptor antagonist. It is a valuable tool in neuroscience research for investigating the roles of specific serotonin receptor subtypes in physiological and pathological processes. Its applications span cell biology and the study of neurotransmission.
- IUPAC
- 1-[10,11-Dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt,Metitepine mesylate salt
- Synonyms
- 1-[10,11-Dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate saltMetitepine mesylate salt

Serotonin Receptor Antagonism
Methiothepin mesylate salt acts as an antagonist at various serotonin (5-HT) receptors, including subtypes like 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT6, and 5-HT7. This makes it useful for dissecting the specific roles of these receptors in the central nervous system.
Neuroscience Research Tool
The compound is employed in preclinical research to investigate the neurobiological underpinnings of various conditions related to neurotransmission. Its selective receptor interaction profile aids in understanding complex signaling pathways.
Cell Signaling Studies
As a modulator of GPCRs, Methiothepin mesylate salt serves as a reagent for studying cell signaling cascades initiated by serotonin receptor activation or blockade.
| Molecular weight | 452.65 |
|---|---|
| Linear formula | C20H24N2S2 · CH3SO3H |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | H2O: soluble13 mg/mL |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methiothepin mesylate salt used for?
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Methiothepin mesylate salt is primarily used as a serotonin receptor antagonist in neuroscience research for studying cell signaling, neurotransmission, and the function of various serotonin receptor subtypes (e.g., 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT6, 5-HT7).
What is the CAS number and formula for Methiothepin mesylate salt?
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The CAS number is 74611-28-2, and the molecular formula is C20H24N2S2 · CH3SO3H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methiothepin mesylate salt with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Methiothepin mesylate salt be handled safely?
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Handle Methiothepin mesylate salt with appropriate personal protective equipment, including eyeshields, gloves, and a respirator filter (type N95 or P1). Refer to the safety data sheet for detailed handling and hazard information. The WGK classification in Germany is 3.
How is Methiothepin mesylate salt packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Packaging, shipping, and export details are available upon request, adhering to all relevant regulations.
How can I request a sample or quote for Methiothepin mesylate salt?
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To request a sample or a quote for Methiothepin mesylate salt, please contact our sales team through the website or by phone. Please specify the quantity required.
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