3-Chloro-4-fluorobenzonitrile
3-Chloro-4-fluorobenzonitrile (CAS 117482-84-5) is a substituted aromatic nitrile with the chemical formula ClC6H3(F)CN and a molecular weight of 155.56 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its specific functional groups allow for diverse chemical transformations, making it a useful intermediate for constructing more complex molecular architectures.
Pharmaceutical Intermediate
3-Chloro-4-fluorobenzonitrile is employed in the synthesis of active pharmaceutical ingredients (APIs). Its structure can be incorporated into drug candidates targeting various therapeutic areas, leveraging the reactivity of both the nitrile group and the halogenated aromatic ring.
Agrochemical Synthesis
This chemical serves as a precursor in the creation of novel agrochemicals, including herbicides, insecticides, and fungicides. The presence of fluorine and chlorine atoms can impart desirable properties such as enhanced efficacy and metabolic stability to the final agrochemical product.
Materials Science Research
As a functionalised aromatic compound, 3-Chloro-4-fluorobenzonitrile may find applications in the development of advanced materials. Its unique electronic and structural properties could be beneficial in creating polymers, liquid crystals, or other functional organic materials.
Organic Synthesis Building Block
Researchers utilise 3-Chloro-4-fluorobenzonitrile as a versatile building block for constructing diverse organic molecules. It enables the introduction of a specific chloro-fluoro-benzonitrile moiety into target compounds via various established synthetic routes.
| Molecular weight | 155.56 |
|---|---|
| Linear formula | ClC6H3(F)CN |
| Assay | 99% |
| Melting point | 69-71 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-fluorobenzonitrile used for?
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3-Chloro-4-fluorobenzonitrile is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 3-Chloro-4-fluorobenzonitrile?
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The CAS number is 117482-84-5 and the chemical formula is ClC6H3(F)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-4-fluorobenzonitrile with an assay of 99%. This product is suitable for research and chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
How should 3-Chloro-4-fluorobenzonitrile be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. This compound is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation and may cause respiratory irritation.
Is 3-Chloro-4-fluorobenzonitrile a controlled substance?
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Based on the provided data, there is no indication that 3-Chloro-4-fluorobenzonitrile is a controlled substance. However, users should always verify local regulations.
How can I request a quote or sample of 3-Chloro-4-fluorobenzonitrile?
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To request a quote or sample, please contact the TSS sales team through our website or by phone, providing your specific requirements.
How is 3-Chloro-4-fluorobenzonitrile packed and shipped?
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3-Chloro-4-fluorobenzonitrile is typically packed in appropriate containers suitable for chemical transport and exported globally by TSS according to international shipping regulations.
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