3-Chloro-4-fluoroiodobenzene
3-Chloro-4-fluoroiodobenzene (CAS: 156150-67-3) is a halogenated aromatic compound with the molecular formula ClC6H3(F)I and a molecular weight of 256.44. This substance serves as a valuable building block in organic synthesis. Its unique combination of chloro, fluoro, and iodo substituents on the benzene ring allows for diverse chemical transformations, making it useful in the development of complex molecules for various research and industrial applications.

Organic Synthesis Intermediate
3-Chloro-4-fluoroiodobenzene is a versatile intermediate used in the synthesis of more complex organic molecules. The presence of three different halogens allows for selective functionalisation through reactions such as Suzuki, Sonogashira, or Ullmann couplings.
Pharmaceutical Research
This compound can be employed in the discovery and development of novel pharmaceutical agents. Its structure may be incorporated into potential drug candidates, leveraging the influence of halogenation on biological activity and pharmacokinetic properties.
Materials Science
The compound's structure may lend itself to applications in materials science, where halogenated aromatics can influence properties like thermal stability or electronic characteristics in polymers or advanced materials.
Agrochemical Development
As a building block, 3-Chloro-4-fluoroiodobenzene may find use in the synthesis of new agrochemicals, including pesticides and herbicides, contributing to crop protection research.
| Molecular weight | 256.44 |
|---|---|
| Linear formula | ClC6H3(F)I |
| Assay | 98% |
| Boiling point | 94-95 °C/15 mmHg(lit.) |
| Density | 2.008 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.604(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-fluoroiodobenzene used for?
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3-Chloro-4-fluoroiodobenzene is primarily used as an intermediate in organic synthesis, particularly in the pharmaceutical, agrochemical, and materials science sectors, for creating more complex molecules.
What is the CAS number and chemical formula for 3-Chloro-4-fluoroiodobenzene?
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The CAS number is 156150-67-3, and the chemical formula is ClC6H3(F)I.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-4-fluoroiodobenzene with an assay of 98%. This product is intended for research and laboratory use. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.
How should 3-Chloro-4-fluoroiodobenzene be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator (e.g., type ABEK filter). It is classified as a skin irritant (H315), eye irritant (H319), and may cause respiratory irritation (H335). Ensure adequate ventilation.
Is 3-Chloro-4-fluoroiodobenzene a controlled substance?
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The provided data does not indicate that 3-Chloro-4-fluoroiodobenzene is a controlled substance.
How is 3-Chloro-4-fluoroiodobenzene packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling packing, shipping, and export in accordance with international regulations for chemical substances.
How can I request a quote or sample for 3-Chloro-4-fluoroiodobenzene?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through our official channels, providing your specific requirements.
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