3-Chloro-4-fluorophenol
3-Chloro-4-fluorophenol (CAS: 2613-23-2), with the molecular formula ClC6H3(F)OH and a molecular weight of 146.55 g/mol, is a halogenated phenol. This chemical compound serves as a valuable intermediate in organic synthesis, particularly in the preparation of complex molecules. It is employed as a building block in the synthesis of various chemical structures, contributing to advancements in materials science and pharmaceutical research. Its specific properties make it useful in targeted chemical transformations.

Synthesis of Flavone and Xanthone Derivatives
3-Chloro-4-fluorophenol has been utilised in the synthesis of 3-chloro-4-fluoro-2′-methoxycarbonyldiphenyl ether. This intermediate is crucial for the subsequent preparation of flavone and xanthone derivatives, important classes of organic compounds.
Organic Synthesis Intermediate
As a fluorinated building block, this compound is instrumental in constructing more complex organic molecules. Its reactivity profile allows for its incorporation into diverse synthetic pathways within chemical research and development.
Aryl Fluorinated Building Block
This chemical falls under the category of Aryl Fluorinated Building Blocks, indicating its utility in introducing fluorinated aromatic moieties into target molecules. Such structures are often sought after in medicinal chemistry and materials science.
| Molecular weight | 146.55 |
|---|---|
| Linear formula | ClC6H3(F)OH |
| Assay | 98% |
| Boiling point | 104 °C/11 mmHg(lit.) |
| Application | 3-Chloro-4-fluorophenol has been used in the preparation of 3-chloro-4-fluoro-2′-methoxycarbonyldiphenyl ether required for the synthesis of flavone and xanthone derivatives1. |
| Melting point | 38-40 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-fluorophenol used for?
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3-Chloro-4-fluorophenol is used as a chemical intermediate in organic synthesis, notably in the preparation of flavone and xanthone derivatives. It serves as an aryl fluorinated building block for creating more complex organic molecules.
What is the CAS number and molecular formula for 3-Chloro-4-fluorophenol?
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The CAS number for 3-Chloro-4-fluorophenol is 2613-23-2, and its molecular formula is ClC6H3(F)OH.
What grade and purity does Tech Serve Solutions supply for 3-Chloro-4-fluorophenol?
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Tech Serve Solutions supplies 3-Chloro-4-fluorophenol with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety hazards associated with 3-Chloro-4-fluorophenol?
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3-Chloro-4-fluorophenol is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle with appropriate ventilation.
How is 3-Chloro-4-fluorophenol packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ensures that 3-Chloro-4-fluorophenol is appropriately packed and handled according to international shipping regulations for chemical substances.
How can I request a quote or sample for 3-Chloro-4-fluorophenol?
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To request a quote or sample of 3-Chloro-4-fluorophenol, please contact the Tech Serve Solutions sales team through our website or via phone. Our experts will assist you with your specific requirements.
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