5-Benzimidazolecarboxylic acid
5-Benzimidazolecarboxylic acid (CAS: 15788-16-6; Formula: C8H6N2O2; MW: 162.15) is a heterocyclic organic compound primarily utilised as a versatile building block in chemical synthesis. Its structure, featuring both benzimidazole and carboxylic acid moieties, makes it a valuable precursor for the development of more complex molecules. This compound is essential for researchers and chemists involved in medicinal chemistry and materials science, enabling the creation of novel derivatives and functional materials.
Preparation of Benzotriazole Esters
5-Benzimidazolecarboxylic acid serves as a key intermediate in the synthesis of 1H-benzoimidazole-5-carboxylic acid benzotriazol-1-yl ester. This ester derivative can be further utilised in various organic transformations.
Synthesis of Amide Derivatives
The compound is employed in the preparation of substituted benzimidazole amides, such as piperidin-1-yl(1-m-tolyl-1H-benzo[d]imidazol-5-yl)methanone. These amides may exhibit interesting pharmacological or material properties.
Heterocyclic Building Block
As a functionalised benzimidazole, it acts as a crucial building block for constructing diverse heterocyclic frameworks. This is vital in the discovery of new chemical entities.
| Molecular weight | 162.15 |
|---|---|
| Empirical formula | C8H6N2O2 |
| Assay | 96% |
| Application | 5-Benzimidazolecarboxylic acid has been used in the preparation of:• 1H-benzoimidazole-5-carboxylic acid benzotriazol-1-yl ester1• piperidin-1-yl(1-m-tolyl-1H-benzo[d]imidazol-5-yl)methanone2 |
| Melting point | >300 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Benzimidazolecarboxylic acid used for?
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5-Benzimidazolecarboxylic acid is primarily used as a building block in chemical synthesis, particularly for preparing ester and amide derivatives of benzimidazole, and for constructing complex heterocyclic structures.
What are the CAS number and formula for 5-Benzimidazolecarboxylic acid?
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The CAS number is 15788-16-6, and the empirical formula is C8H6N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Benzimidazolecarboxylic acid with a minimum assay of 96%. This product is suitable for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should 5-Benzimidazolecarboxylic acid be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. The compound may cause skin irritation, eye irritation, and respiratory irritation (H315, H319, H335).
How is 5-Benzimidazolecarboxylic acid packed and shipped?
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This chemical is carefully packed for secure transport and is available for global export by Tech Serve Solutions, a specialist supplier established in 1998.
How can I request a sample or quote for 5-Benzimidazolecarboxylic acid?
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Please contact our sales department via the website or by phone to request a sample or a formal quotation for 5-Benzimidazolecarboxylic acid.
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