5-Azidopentanoic acid
5-Azidopentanoic acid (CAS 79583-98-5, C5H9N3O2) is a bifunctional organic compound with a molecular weight of 143.14 g/mol. It features both a terminal azide group and a carboxylic acid moiety, making it a versatile building block in organic synthesis. Its primary applications lie in chemical synthesis and chemical biology, particularly for creating complex molecules and for conjugation chemistry.
- IUPAC
- 5-Azidovalerianic acid

Organic Synthesis
This compound serves as a valuable intermediate in the synthesis of diverse organic molecules. The presence of both azide and carboxylic acid functionalities allows for a range of chemical transformations and the introduction of nitrogen-containing groups.
Chemical Biology
5-Azidopentanoic acid is utilised in chemical biology for labelling and modification of biomolecules. Its azide group is reactive in click chemistry reactions, enabling bioconjugation and the study of biological processes.
Building Block Chemistry
As a C1 to C5 building block, it is integral for constructing more complex structures. Its application extends to nitrogen compound synthesis and as a reagent in conjugation chemistry involving azides and alkynes.
| Molecular weight | 143.14 |
|---|---|
| Empirical formula | C5H9N3O2 |
| Assay | ≥97.0% (TLC)≥97.0%97.0-103.0% (calc. on dry substance, T) |
| Loss on drying | ≤10% loss on drying |
| Storage temperature | −20°C |

Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Azidopentanoic acid used for?
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5-Azidopentanoic acid is primarily used as a building block in organic synthesis and for applications in chemical biology and conjugation chemistry.
What are the CAS number and formula for 5-Azidopentanoic acid?
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The CAS number for 5-Azidopentanoic acid is 79583-98-5, and its empirical formula is C5H9N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Azidopentanoic acid with an assay of ≥97.0% (TLC) or ≥97.0% (calc. on dry substance, T). TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling 5-Azidopentanoic acid?
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5-Azidopentanoic acid is classified with GHS08 symbol and a Warning signal word, carrying the hazard statement H351 (Suspected of causing cancer). Appropriate personal protective equipment, including eyeshields and suitable respirator filters, should be used, and handling should be done with caution.
How is 5-Azidopentanoic acid shipped and exported?
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As a global supplier and exporter, Tech Serve Solutions ships and exports 5-Azidopentanoic acid according to international regulations for chemical transport. Storage at -20°C is recommended.
How can I request a quote or sample for 5-Azidopentanoic acid?
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You can request a quote or a sample of 5-Azidopentanoic acid by contacting the Tech Serve Solutions sales team directly through our website or designated contact channels.
How is 5-Azidopentanoic acid synthesized?
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Published preparations of 5-Azidopentanoic acid are documented in the chemical literature and patent records — see the synthesis and sourcing section on this page for reference links. Tech Serve Solutions supplies 5-Azidopentanoic acid ready to use; request a quote for current grades and pack sizes.
How 5-Azidopentanoic acid (79583-98-5) is synthesized — and where to buy it
5-Azidopentanoic acid is a C5 azide–acid bifunctional linker for click chemistry (CuAAC/SPAAC) and bioconjugation, pairing a carboxylic-acid handle with an azide terminus.
Published preparations include hydroazidation of the corresponding olefin (see the patent literature below) and classical azide displacement chemistry. [US 11,708,320 — hydroazidation of olefins]
Published synthesis & references
Why make it?
Running azide chemistry in-house carries hydrazoic-acid and self-reactivity risk. Skip that step — we supply the linker tested, with SDS and a Certificate of Analysis per batch.
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