5-Azacytosine

CAS 931-86-2C3H4N4OChemical Synthesis

5-Azacytosine (CAS: 931-86-2; Formula: C3H4N4O) is a heterocyclic compound with a molecular weight of 112.09 g/mol. It serves as a valuable building block in chemical synthesis, particularly in the preparation of nucleoside analogs and in reactions involving oxide radical ions. This triazine derivative also exhibits potential as an antitumor and antiproliferative agent against specific human leukemia cells.

IUPAC: 2-Hydroxy-4-aminotriazine,4-Amino-1,3,5-triazin-2-ol,4-Amino-1,3,5-triazin-2-one,4-Amino-2-hydroxy-1,3,5-triazine,NSC 51100,NSC 54006
Synonyms: 2-Hydroxy-4-aminotriazine4-Amino-1,3,5-triazin-2-ol4-Amino-1,3,5-triazin-2-one4-Amino-2-hydroxy-1,3,5-triazineNSC 51100NSC 54006

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5-Azacytosine (C3H4N4O) — chemical structure, CAS 931-86-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisHeterocyclic Building BlocksTriazines

01 /Applications

Nucleoside Analog Synthesis

5-Azacytosine is utilised as a reactant in the enzymic synthesis of novel nucleoside analogs. This process employs immobilized 2′-deoxyribosyltransferase from Lactobacillus reuteri.

Chemical Reactions

This compound participates in reactions with oxide radical ions. It is a versatile building block for organic synthesis, particularly within the realm of heterocyclic chemistry.

Potential Biological Applications

Research indicates that 5-Azacytosine may act as a potential antitumor and antiproliferative agent. Studies have explored its efficacy against certain human leukemia cell lines.

02 /Properties

Molecular weight	112.09
Empirical formula	C3H4N4O
Application	Reactant for:• Enzymic synthesis of nucleoside analogs using immobilized 2′-deoxyribosyltransferase from Lactobacillus reuteri1• Reactions with oxide radical ion2• Potential antitumor and antiproliferative agent against human leukemia cells3
Melting point	>300 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

931-86-2

MDL number

MFCD00006033

PubChem substance

24888369

Beilstein registry

116378

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Azacytosine used for?

5-Azacytosine is primarily used as a reactant in the enzymic synthesis of nucleoside analogs, in reactions with oxide radical ions, and is explored for its potential as an antitumor and antiproliferative agent.

What is the CAS number and formula for 5-Azacytosine?

The CAS number for 5-Azacytosine is 931-86-2, and its empirical formula is C3H4N4O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 5-Azacytosine for research and chemical synthesis purposes. The specific grade and purity are available upon request; TSS does not represent this product as USP, BP, EP, or for pharmaceutical, food, or nutraceutical use.

What are the safety considerations for handling 5-Azacytosine?

5-Azacytosine is classified as harmful if swallowed (H302). When handling, it is essential to use appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter.