3-Chloro-4-fluoroaniline
3-Chloro-4-fluoroaniline (CAS 367-21-5, C6H3ClFN) is a key aromatic amine building block with a molecular weight of 145.56 g/mol. This fluorinated compound serves as a valuable intermediate in the synthesis of complex organic molecules. It is particularly useful in the development of pharmaceuticals and agrochemicals, owing to the specific reactivity imparted by the chlorine and fluorine substituents on the aniline ring.
Pharmaceutical Intermediate
3-Chloro-4-fluoroaniline is employed in the synthesis of active pharmaceutical ingredients (APIs). Its unique structure allows for the introduction of specific pharmacophores, contributing to the development of novel therapeutic agents.
Agrochemical Synthesis
This chemical serves as a building block in the production of pesticides and herbicides. The fluorinated and chlorinated aromatic moiety can be crucial for the biological activity and stability of agrochemical products.
Organic Synthesis
As a versatile organic building block, 3-Chloro-4-fluoroaniline is used in various chemical transformations. It is a valuable reagent for researchers and manufacturers in the field of fine chemicals and materials science.
| Molecular weight | 145.56 |
|---|---|
| Linear formula | ClC6H3(F)NH2 |
| Assay | 98% |
| Boiling point | 227-228 °C(lit.) |
| Melting point | 42-44 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-33 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-4-fluoroaniline used for?
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3-Chloro-4-fluoroaniline is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other complex organic molecules. It is a valuable building block in organic synthesis.
What are the CAS number and chemical formula for 3-Chloro-4-fluoroaniline?
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The CAS number for 3-Chloro-4-fluoroaniline is 367-21-5, and its chemical formula is ClC6H3(F)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-4-fluoroaniline with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the main hazards associated with 3-Chloro-4-fluoroaniline?
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3-Chloro-4-fluoroaniline is classified as toxic if swallowed, in contact with skin, or if inhaled (H301-H311-H331). It may also cause damage to organs through prolonged or repeated exposure (H373). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges.
How is 3-Chloro-4-fluoroaniline typically packed and exported?
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3-Chloro-4-fluoroaniline is packed according to UN 2811 6.1 / PGII regulations for safe transport and is exported globally by Tech Serve Solutions.
How can I request a quote or sample of 3-Chloro-4-fluoroaniline?
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To request a quote or a sample of 3-Chloro-4-fluoroaniline, please contact our sales department through the website or by phone.
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